| anaesthesia, local | Anaesthesia confined to one part of the body. Infiltration anaesthesia produces local anaesthesia by deposition of a local anaesthesia solution in the area of small, terminal nerve endings. (12 Dec 1998) |
|---|---|
| anaesthetics, local | Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fibre. In contact with a nerve trunk, these anaesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. Nearly all local anaesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. They are commonly used not only in the peripheral nervous system, but also for spinal anaesthesia. The many drugs that have local anaesthetic actions as a side effect but are not used for their local anaesthetic action are not included here. (12 Dec 1998) |
| anti-infective agents, local | Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from disinfectants, which are used on inanimate objects. (12 Dec 1998) |
| neoplasm recurrence, local | The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site. (12 Dec 1998) |
| local | Restricted to or pertaining to one spot or part, not general. Origin: L. Localis (18 Nov 1997) |
| local anaemia | Anaemia resulting from a decreased supply of blood to a part, as in the occlusion of a vessel. (05 Mar 2000) |
| local anaesthesia | The use of a local anaesthetic (usually injected into the tissue) results in a small region of anaesthesia (numbness). Lidocaine (Xylocaine) or (Marcaine) are commonly used. Origin: Gr. Aisthesis = sensation (27 Sep 1997) |
| local anaesthetic | The use of a local anaesthetic (usually injected into the tissue) results in a small region of anaesthesia (numbness). Lidocaine (Xylocaine) or (Marcaine) are commonly used. (27 Sep 1997) |
| local anaesthetic reaction | A toxic reaction due to absorption of local anaesthetic drug during regional anaesthesia, ranging from drowsiness to convulsions and cardiovascular collapse. (05 Mar 2000) |
| local anaesthetics | Drugs used for the interruption of the nerve transmission of pain sensations. They act at the site of application to prevent perception of pain; examples include procaine and lidocaine. (05 Mar 2000) |
| local anaphylaxis | The immediate, transient kind of response that follows the injection of antigen (allergen) into the skin of a sensitised individual and is limited to the area surrounding the site of inoculation. See: skin test. (05 Mar 2000) |
| local area networks | Communications networks connecting various hardware devices together within or between buildings by means of a continuous cable or voice data telephone system. (12 Dec 1998) |
| local asphyxia | Stagnation of the circulation, sometimes resulting in local gangrene, especially of the fingers; one of the symptoms usually associated with Raynaud's disease. (05 Mar 2000) |
| local bloodletting | Removing blood from the smaller vessels, formerly by a cupping glass or by leeching. (05 Mar 2000) |
| local circuit theory | <physiology> A generally accepted model for neuronal conduction, by which depolarisation of a small region of a neuronal plasma membrane produces transmembrane currents in the neighbouring regions, tending to depolarise them. As the sodium channels are voltage gated, the depolarisation causes further channels to open, thus propagating the action potential. (18 Nov 1997) |