| toxic goiter | A goiter that forms an excessive secretion, causing signs and symptoms of hyperthyroidism. (05 Mar 2000) |
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| toxic multinodular goiter | Condition in which the thyroid gland contains multiple lumps (nodules) that are overactive, produce excess thyroid hormones and thereby cause hyperthyroidism. This condition is also known as parry's disease or plummer's disease. (12 Dec 1998) |
| endemic goiter | Goiter, usually of simple type, prevalent in certain regions where dietary intake of iodine is suboptimal. (05 Mar 2000) |
| exophthalmic goiter | Any of the various forms of hyperthyroidism in which the thyroid gland is enlarged and exophthalmos is present. (05 Mar 2000) |
| familial goiter | A group of heritable thyroid disorders in which goiter is commonly apparent first during childhood; often associated with skeletal and/or mental retardation, and with other signs of hypothyroidism that may develop with age. Various types of familial goiter have been identified: 1) iodide transport defect, in which the gland is unable to concentrate iodide; 2) organification defect, in which the iodination of tyrosine is defective; 3) Pendred's syndrome; 4) coupling defect, in which cretinism results from defective coupling of iodotyrosines to form iodothyronines; 5) iodotyrosine deiodinase defect, in which deiodination of iodotyrosine is defective, considerable glandular loss of these hormonal precursors occurs, and cretinism may be present; 6) plasma iodoprotein disorder, in which an abnormal iodinated serum protein that is insoluble in acidic butanol is present; 7) hereditary hyperthyroidism. (05 Mar 2000) |
| fibrous goiter | A firm hyperplasia of the thyroid and its capsule. (05 Mar 2000) |
| follicular goiter | A form of goiter in which there is a great increase in the follicles with proliferation of the epithelium. Synonym: follicular goiter. (05 Mar 2000) |
| lingual goiter | A tumour of thyroid tissue involving the embryonic rudiment at the base of the tongue. (05 Mar 2000) |
| lymphadenoid goiter | <endocrinology> Inflammation of the thyroid gland without the formation of pus. Noninfectious nonbacterial thyroid inflammation. (27 Sep 1997) |