| 영문 | radiation therapy | 한글 | 방사선요법 |
|---|---|---|---|
| 설명 | X선, γ선의 전자방사선이나 전자선, 양자선, 중성자선 등의 입자방사선을 이용해, 주로 악성 종양 치료를 목적으로 하는 치료법이다. 암세포가 주위의 정상세포보다도 방사선 감수성이 높은 점을 이용하여, 정상세포의 손상을 가능한 한 최소로 억제하면서 암세포를 파괴한다. 사용되는 방사선에는 밀봉소선원에서 나오는 γ선, 직선가속기에서 얻어지는 고에너지 X선과 전자선, 텔레코발트장치에 의한 60Co의 γ선과, 베타트론에 의한 전자선, 사이크로트론에서 얻어지는 양자선, 중성자선 등이 있다. |
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| 영문 | radiation therapy | 한글 | 방사선치료 |
|---|---|---|---|
| 설명 | 방사선의 살균효과나 세포를 죽이는 효과를 치료에 이용하는 방법으로, 좁은 의미로 암의 방사선치료를 의미한다. 암에 대한 방사선치료는 암세포를 죽이는데 효과가 큰 베타선을 주로 사용한다. 하지만, 이런 방사선치료는 정상세포에도 큰 영향을 끼쳐 이에 따른 기능의 장애를 가져올 수 있다. 따라서 방사선치료에 있어서는 단지 그 암세포에 대한 작용뿐만 아니라, 정상세포에 대한 작용도 고려하여 시행한다. |
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| 영문 | speech therapy | 한글 | 언어치료 |
|---|---|---|---|
| 설명 | 말을 정확하게 발음할 수 없거나 더듬는 환자에게 발음, 대화 따위의 훈련을 전문적으로 행하는 치료법. |
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| 영문 | therapy | 한글 | 요법 |
|---|---|---|---|
| 설명 | 병을 낫게 하는 것 또는 그 방법. |
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| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| CDI | cell-directed inhibitor; central or chronic diabetes insipidus; Children's Depression Inventory; col... |
|---|---|
| DAD | delayed afterdepolarization; diffuse alveolar damage; dispense as directed |
| DSUH | directed suggestion under hypnosis |
| MEDIHC | Military Experience Directed Into Health Careers |
| ODB | opiate-directed behavior |
| R enzyme | <enzyme> An enzyme with action similar to that of isoamylase; it cleaves 1,6-alpha-glucosidic linkages in pullalan, amylopectin, and glycogen, and in alpha-and beta-amylase limit-dextrins of amylopectin and glycogen. Compare: isoamylase. Synonym: limit dextrinase, pullulanase, R enzyme. (05 Mar 2000) |
|---|---|
| repair enzyme | <enzyme, molecular biology> An enzyme that can catalyze the repair of damaged DNA; e.g., DNA ligase. (05 Mar 2000) |
| repressible enzyme | <biochemistry> In bacteria, an enzyme whose creation is inhibited when its reaction product is plentiful. (09 Oct 1997) |
| respiratory enzyme | One of those enzyme's in tissues that is a part of an oxidation-reduction system accomplishing the conversion of substrates to CO2 and H2O and the transfer of the electrons removed to O2. (05 Mar 2000) |
| respiratory enzyme complexes | <biochemistry> The enzymes that make up the respiratory chain: NADH Q reductase, succinate Q reductase, cytochrome reductase, cytochrome C and cytochrome oxidase. (18 Nov 1997) |
| glycogen debranching enzyme system | 1,4-alpha-d-glucan-1,4-alpha-d-glucan 4-alpha-d-glucosyltransferase/dextrin 6 alpha-d-glucanohydrolase. An enzyme system having both 4-alpha-glucanotransferase (ec 2.4.1.25) and amylo-1,6-glucosidase (ec 3.2.1.33) activities. As a transferase it transfers a segment of a 1,4-alpha-d-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-d-glucan. As a glucosidase it catalyses the endohydrolysis of 1,6-alpha-d-glucoside linkages at points of branching in chains of 1,4-linked alpha-d-glucose residues. Amylo-1,6-glucosidase activity is deficient in glycogen storage disease type III. (12 Dec 1998) |
| restriction enzyme | <enzyme, molecular biology> Class of bacterial enzymes that cut DNA at specific sites. In bacteria their function is to destroy foreign DNA, such as that of bacteriophages (host DNA is specifically modified at these sites). Type I restriction endonucleases occur as a complex with the methylase and a polypeptide that binds to the recognition site on DNA. They are often not very specific and cut at a remote site. Type II restriction endonucleases are the classic experimental tools. They have very specific recognition and cutting sites. The recognition sites are short, 4-8 nucleotides and are usually palindromic sequences. Because both strands have the same sequence running in opposite directions the enzymes make double stranded breaks, which, if the site of cleavage is off centre, generates fragments with short single stranded tails, these can hybridise to the tails of other fragments and are called sticky ends. They are generally named according to the bacterium from which they were isolated (first letter of genus name and the first two letters of the specific name). The bacterial strain is identified next and multiple enzymes are given Roman numerals. For example the two enzymes isolated from the R strain of E. Coli are designated Eco RI and Eco RII. (10 Mar 1998) |
| restriction enzyme cutting site | <molecular biology> A specific nucleotide sequence of DNA at which a particular restriction enzyme cuts the DNA. Some sites occur frequently in DNA (for example, every several hundred basepairs), others much less frequently (rare-cutter, for example, every 10,000 base pairs). (10 Mar 1998) |
| restriction enzyme, endonuclease | A protein that recognises specific, short nucleotide sequences and cuts DNA at those sites. Bacteria contain over 400 such enzymes that recognise and cut over 100 different DNA sequences. See restriction enzyme cutting site. (05 Mar 2000) |
| P enzyme | <enzyme> Enzyme that catalyses the sequential removal of glycosyl residues from glycogen to yield one glucose-1-phosphate per reaction. Its activity is controlled by phosphorylation (by phosphorylase kinase). (21 Jun 2000) |
| membrane enzyme | <enzyme> An enzyme present or embedded in a biomembrane. (05 Mar 2000) |
| RNA enzyme | <molecular biology> Often referred to as RNA with catalytic capacity, an enzyme made of nucleic acid not protein that catalyse chemical reactions, often the breakdown of other RNAs. Of particular interest because of the implications for self replicating systems in the earliest stages of the evolution of (terrestrial) life. Their discovery in the mid-1980s refuted the concept that only proteins could be biological catalysts. There is potential for their use as pharmaceuticals and industrial catalysts. (13 Nov 1997) |
| methionine-activating enzyme | <enzyme> An enzyme that catalyses the synthesis of s-adenosylmethionine from methionine and ATP. Chemical name: ATP:L-methionine S-adenosyltransferase Registry number: EC 2.5.1.6 (12 Dec 1998) |
| microparticle enzyme immunoassay | A technique in which the solid-phase support consists of very small microparticles in liquid suspension. Specific reagent antibodies are covalently bound to the microparticles. Antigen, if present, is then "sandwiched" between bound antibodies and antigen-specific, enzyme-labelled antibodies. Antigen-antibody complexes are detected and quantitated by analysis of fluorescence from the enzyme-substrate interaction. Acronym: MEIA (05 Mar 2000) |
| citrate cleavage enzyme | ATP citrate (pro-3S)-lyase |