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aspartic proteinases <enzyme> A sub-subclass of proteolytic enzymes which, because of the involvement of an acidic residue in the catalytic process, hydrolyzes the peptide bonds at a pH optimum below 5.
Registry number: EC 3.4.23
(12 Dec 1998)
aspartokinase homoserine dehydrogenase An enzyme complex consisting of aspartokinase, and homoserine dehydrogenase, The complex has been isolated from e. Coli and consists of four identical subunits with a molecular weight of 85,000. The enzyme complex is involved in the biosynthesis of amino acids of the aspartate family.
(12 Dec 1998)
aspartyl The aminoacyl radical of aspartic acid.
(05 Mar 2000)
aspartylglucosylaminase <enzyme> An enzyme that catalyses the conversion of n(4)-(beta-n-acetyl-d-glucosaminyl)-l-asparagine and water to n-acetyl-beta-d-glucosaminylamine and l-aspartate. It acts only on asparagine oligosaccharides containing one amino acid, i.e. The asparagine has free alpha-amino and alpha-carboxyl groups.
Chemical name: N(4)-(beta-N-Acetyl-D-glucosaminyl)-L-asparagine amidohydrolase
Registry number: EC 3.5.1.26
(12 Dec 1998)
aspartylglycosamine Generic term for compounds of asparagine and a 2-amino sugar; e.g., beta-aspartyl(acetylglucosamine).
(05 Mar 2000)
aspartylglycosaminidase A hydrolytic enzyme that cleaves off L-aspartate from aspartylglycosamines. A deficiency of aspartylglycosaminidase can result in aspartylglycosaminuria.
(05 Mar 2000)
aspartylglycosaminuria One of the disorders of glycoprotein catabolism resulting from the absence of aspartylglycosamine amidohydrolase, characterised by aspartylglycosamine in the urine and spinal fluid. Symptoms develop in the first months of life, with recurrent infections and diarrhoea. Mental retardation, coarse facial features, and skeletal abnormalities are evident by adolescence.
(05 Mar 2000)
aspartyllysine peptidase <enzyme> From human intestinal brush border; stabilised by zn+2
Registry number: EC 3.4.13.-
Synonym: zn-stable aspartyllysine peptidase
(26 Jun 1999)
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