| 4-hydroxybenzoate synthase | <chemical> Complex associated with mitochondrial membranes of roots of cucumis sativus; converts p-coumaric acid to p-hydroxybenzoic acid; mechanism of multi-step reaction unclear Chemical name: synthase, p-hydroxybenzoate Synonym: para-hydroxybenzoate synthase, p-hydroxybenzoate synthase (26 Jun 1999) |
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| 4-hydroxybenzoate-3-monooxygenase | <enzyme> A flavoprotein that catalyses the synthesis of protocatechuic acid from 4-hydroxybenzoate in the presence of molecular oxygen. Chemical name: 4-Hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating) Registry number: EC 1.14.13.2 (12 Dec 1998) |
| 4-hydroxybenzoyl-CoA hydrolase | <enzyme> Final enzyme in the degradation of 4-chlorobenzoic acid by pseudomonas; liberates 4-hydroxybenzoic acid; amino acid sequence has been determined Registry number: EC 3.1.2.- Synonym: 4-hydroxybenzoyl-coenzyme a thioesterase, 4-hba-CoA thioesterase (26 Jun 1999) |
| 4-hydroxybutyrate CoA-transferase | <enzyme> Forms 4-hydroxybutyryl-CoA from 4-hydroxybutyrate and acetyl-CoA Registry number: EC 2.8.3.- Synonym: 4-hydroxybutyrate coenzyme a transferase (26 Jun 1999) |
| 4-hydroxybutyric aciduria | Elevated levels of 4-hydroxybutyrate in the urine. An inherited disorder that can lead to hypotonia and mental retardation. (05 Mar 2000) |
| 4-hydroxybutyryl-CoA dehydratase | <enzyme> Forms vinylacetyl-CoA from 4-hydroxybutyryl-CoA Registry number: EC 4.2.1.- Synonym: gamma-hydroxybutyryl-CoA dehydratase (26 Jun 1999) |
| 4-hydroxycoumarins | <chemical> Substances found in many plants, containing the 4-hydroxycoumarin radical. They interfere with vitamin k and the blood clotting mechanism, are tightly protein-bound, inhibit mitochondrial and microsomal enzymes, and are used as oral anticoagulant. Pharmacological action: anticoagulant, enzyme inhibitors. (12 Dec 1998) |
| 4-hydroxyisophthalate hydroxylase | <enzyme> Converts 4-hydroxyisophthalate to protocatechuate. Registry number: EC 1.14.13.- (26 Jun 1999) |
| 4-hydroxyphenylacetate 3-monooxygenase | <enzyme> 4-hydroxyphenylacetate in the presence of NADH and oxygen yields 3,4-dihydroxyphenylacetate Registry number: EC 1.14.13.3 Synonym: 4-hpa hydroxylase, hpab protein, 4-hydroxyphenylacetic acid hydroxylase (26 Jun 1999) |
| 4-hydroxyphenylpyruvate dioxygenase | <enzyme> An enzyme that catalyses the conversion of 4-hydroxyphenylpyruvate plus oxygen to homogentisic acid and carbon dioxide. Chemical name: 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating) Registry number: EC 1.13.11.27 (12 Dec 1998) |
| 4-hydroxyproline | 4-Hydroxy-2-pyrrolidinecarboxylic acid;the trans-l-isomer is an imino acid found among the hydrolysis products of collagen; not found in proteins other than those of connective tissue. A vitamin C deficiency will result in impaired formation of hydroxyproline. (05 Mar 2000) |
| 4-hydroxyproline oxidase | A flavoenzyme that catalyses the conversion of 4-hydroxyproline to d'-pyrroline-3-hydroxy-5-carboxylate using FAD; this enzyme appears to be deficient in individuals with hyperhydroxyprolinaemia, an enzyme that catalyses the reaction of 4-hydroxyproline with NAD+ to form NADH and 4-oxoproline. Synonym: 4-oxoproline reductase. (05 Mar 2000) |
| 4-imidazolone-5-propionate | An intermediate in histidine degradation; seen in reduced levels in urocanic aciduria. (05 Mar 2000) |
| 4-methoxybenzoic acid | A crystalline volatile acid obtained from anise; its compounds are the antiseptic anisates. Synonym: 4-methoxybenzoic acid. (05 Mar 2000) |
| 4-methyl sterol demethylase | <chemical> This term is used to describe 10 reactions in the collective processes of monooxygenation, decarboxylation and reduction, which, together account for the conversion of each of the two 4-methyl groups of lanosterol to carbon dioxide Chemical name: demethylase, methyl sterol Synonym: 4,4-dimethylzymosterol monooxygenase, sterol 4-demethylase (26 Jun 1999) |