| Alzheimer's disease | <disease> A progressive, neurodegenerative disease characterised by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. The cause of nerve cell death is unknown but the cells are recognised by the appearance of unusual helical protein filaments in the nerve cells (neurofibrillary tangles) and by degeneration in cortical regions of brain, especially frontal and temporal lobes. Alzheimer's disease is the most common cause of dementia. (22 May 1997) |
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| anarthritic rheumatoid disease | Rheumatoid disease without arthritis. (05 Mar 2000) |
| Anders' disease | <disease> A disease accompanied by painful localised fatty swellings and by various nerve lesions. It is usually seen in women and may cause death from pulmonary complications. (12 Dec 1998) |
| Andersen's disease | Familial cirrhosis of the liver with storage of abnormal glycogen; glycogenosis due to deficiency of 1,4-alpha-glucan branching enzyme, resulting in accumulation of abnormal glycogen with long inner and outer chains in liver, kidney, muscle, and other tissues. Synonym: Andersen's disease. (05 Mar 2000) |
| antibody deficiency disease | <syndrome> Any of a group of disorders associated with a defective antibody production due to defects in the B-type lymphocyte system or in T-type lymphocytes; chief manifestation is an increased susceptibility to infection by various microorganisms. See: agammaglobulinaemia, hypogammaglobulinaemia, immunodeficiency. Synonym: antibody deficiency disease. (05 Mar 2000) |
| anti-glomerular basement membrane disease | Glomerulonephritis, usually of a generalised proliferative crescent-forming histologic type with a rapidly progressive course, marked by circulating anti-gbm antibodies and linear deposits of immunoglobulin and complement along the glomerular basement membrane. When associated with pulmonary haemorrhage the condition is called goodpasture syndrome. (12 Dec 1998) |
| aortoiliac occlusive disease | Obstruction of the abdominal aorta and its main branches by atherosclerosis. (05 Mar 2000) |
| Aran-Duchenne disease | A serious neurologic disease that results from the progressive degeneration of the motor neurons. (27 Sep 1997) |
| asherman disease | <radiology> Uterine synechiae, linear, lucent defects in uterus on HSG, usually secondary to endometrial trauma (D&C, etc.) (12 Dec 1998) |
| atherosclerotic vascular disease | <cardiology> The progressive narrowing and hardening of the arteries over time. This is known to occur to some degree with aging, but other risk factors that accelerate this process have been identified. These factors include: high cholesterol, high blood pressure, smoking, diabetes and family history for atherosclerotic disease. (27 Sep 1997) |
| Aujeszky's disease | A highly contagious herpes virus infection affecting the central nervous system of swine, cattle, dogs, cats, rats, and other animals. (12 Dec 1998) |
| Aujeszky's disease virus | A herpesvirus causing pseudorabies in swine. Synonym: Aujeszky's disease virus. (05 Mar 2000) |
| Australian X disease | A severe encephalitis with a high mortality rate occurring in the Murray Valley of Australia; the disease is most severe in children and is characterised by headache, fever, malaise, drowsiness or convulsions, and rigidity of the neck; extensive brain damage may result; it is caused by the Murray Valley encephalitis virus (genus Flavivirus). Synonym: Australian X disease, Australian X encephalitis. (05 Mar 2000) |
| Australian X disease virus | A group B arbovirus of the genus Flavivirus that causes Murray Valley encephalitis; it is transmitted by Culex mosquitoes, and also infects birds and horses. Synonym: Australian X disease virus, MVE virus. (05 Mar 2000) |
| autoimmune disease | <disease> A disease process that involves the production of host antibodies to host tissue. (27 Sep 1997) |