| glycuronic acid | <biochemistry> The uronic acid of a sugar in which the terminal carbon is oxidised to a carboxyl group. (05 Mar 2000) |
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| glycyrrhetinic acid | <chemical> 3-beta-hydroxy-11-oxoolean-12-en-30-oic acid. A product from glycyrrhiza glabra l. Leguminosae with some antiallergic, antibacterial, and antiviral properties. It is used topically for allergic or infectious skin inflammation and orally for its aldosterone effects in electrolyte regulation. Pharmacological action: anti-inflammatory agent, topical. Chemical name: Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3beta,20beta)- (12 Dec 1998) |
| glycyrrhizic acid | <chemical, drug> A widely used anti-inflammatory agent isolated from the licorice root. It is metabolised to glycyrrhetic acid, which inhibits 11 beta-hydroxysteroid dehydrogenase and other enzymes involved in the metabolism of corticosteroids. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, oedema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system. Pharmacological action: anti-infective agents, non-steroidal anti-inflammatory agents, antifungal agents, antiviral agents. Chemical name: alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl- (12 Dec 1998) |
| penicillanic acid | <chemical> 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.1)heptane-2-carboxylic acid. A building block of penicillin, devoid of significant antibacterial activity. Pharmacological action: penicillins. Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, (2S-cis)- (12 Dec 1998) |
| penicillic acid | <chemical> 3-methoxy-5-methyl-4-oxo-2,5-hexadienoic acid (in tautomeric equilibrium with its lactone). A mycotoxin with antibiotic and carcinogenic activity produced by various strains of penicillium, by aspergillus ochraceus and aspergillus melleus. Has been found in tobacco, sausages, and corn. Pharmacological action: carcinogens, penicillins. Chemical name: 2,5-Hexadienoic acid, 3-methoxy-5-methyl-4-oxo- (12 Dec 1998) |
| glyoxylic acid | OHC-COOH;produced by the action of glycine dehydrogenases upon glycine or sarcosine, or from allantoic acid by allantoicase or via alanine:glyoxylate aminotransferase. Synonym: oxoacetic acid. (05 Mar 2000) |
| glyoxylic acid cycle | A catabolic cycle in plants and microorganisms like that of the tricarboxylic acid cycle in animals; its key reaction is the condensation of acetyl-CoA with glyoxylic acid to malic acid (analogous to the condensation of acetyl-CoA and oxaloacetic acid to form citric acid in the tricarboxylic acid cycle). Synonym: Krebs-Kornberg cycle. (05 Mar 2000) |
| penicilloic acid | Alkali and bacterial degradation product of a penicillin, resulting from hydrolysis of the 1,7 bond. (05 Mar 2000) |
| cerebronic acid | 2-Hydroxylignoceric acid, 2-hydroxytetraeicosanoic acid; CH3-(CH2)21-CHOH-COOH. A constituent of phrenosin (cerebron) and other glycolipids. Synonym: phrenosinic acid. (05 Mar 2000) |
| melissic acid | Found in waxes. Origin: G. Melissa, bee + -ic (05 Mar 2000) |
| pentanoic acid | CH3(CH2)3COOH;normal aliphatic acid; distilled from valerian; some of its salts are used in medicine; found in human colon. Synonym: pentanoic acid. (05 Mar 2000) |
| cerotinic acid | CH3-(CH2)24 -COOH; n-hexacosanoic acid;a long-chain fatty acid found in natural waxes and in certain lipids. (05 Mar 2000) |
| pentetic acid | A pentaacetic acid triamine with affinity for heavy metals; used as the calcium sodium chelate in the treatment of iron-storage disease and poisoning from heavy metals and radioactive metals. See: ethylenediaminetetraacetic acid. (05 Mar 2000) |
| retinoic acid | <biochemistry> The aldehyde (retinal) has long been known to be involved in photoreception, but retinoic acid has other roles. There are cytoplasmic retinoic acid binding proteins and retinoic acid response elements that regulate gene transcription. Retinoic acid is thought to be a morphogen in chick limb bud development and in early development of the chick that probably accounts for its potent teratogenic action. Synonym: vitamin A. (03 Jul 1999) |
| retinoic acid 4-hydroxylase | <enzyme> Catalyses the hydroxylation of all-trans retinoic acid to 4-hydroxyretinoic acid Registry number: EC 1.14.- Synonym: ra-4-hydroxylase, cytochrome p450 4-hydroxylase, cyp450 4-hydroxylase (26 Jun 1999) |