| cirsophthalmia | Varicose dilation of the conjunctival blood vessels. Origin: G. Kirsos, varix, + ophthalmos, eye (05 Mar 2000) |
|---|---|
| cirsotome | An obsolete term for cutting instrument used in operating upon varicose veins. (05 Mar 2000) |
| cirsotomy | An obsolete term for treatment of varicose veins by multiple incisions. Origin: G. Kirsos, varix, + tome, incision (05 Mar 2000) |
| CIS | <abbreviation> Carcinoma in situ. (05 Mar 2000) |
| cis acting | <molecular biology> Having to do with a genetic element (such as a promoter or other regulatory locus) having an effect (like promotion or suppression) on two unrelated targets (such as genes) on the same chromosome as a result of their relative positions on the chromosome. A gene which regulates the transcription into mRNA of other genes nearby on the same chromosome by binding protein transcription factors which are necessary to turn transcription on or off. (09 Oct 1997) |
| cis activation | <molecular biology> Activation of a gene by an activator located on the same chromosome i.e. Not by a diffusible product. (18 Nov 1997) |
| cis configuration | <molecular biology> The configuration of an organic molecule containing a double bond between two carbon atoms, where the largest, most complex R groups are on the same side: H H \ / C=C / \ H3C CH3 -OR-The configuration of an organic molecule containing a ring, where the largest, most complex R groups are on the same side: H H | ___ \ / | // \\ [ring viewed edge-on] | \___/ / \ | /---\ H3C CH3 | H3C CH3. A genetics term meaning an event or a gene whose action occurs on the same chromosome. Two mutations in different genes coding for the same phenotype which are on the same chromosome (as opposed to the trans configuration where each homologue has one of the mutations). Compare: trans configuration. (11 Jan 1998) |
| cis dominance | <molecular biology> When a gene or promoter affects only gene activity in the DNA duplex molecule in which it is placed the effect is referred to as cis, as opposed to trans effects when a gene or promoter on one DNA molecule can affect genes on another DNA molecule. Cis dominance is seen only when the appropriate pair or set of genes are all cis to each other. (18 Nov 1997) |
| cis trans test | <molecular biology> The complementation test with two or more interacting genes placed in cis and in trans relationships to each other. A double mutant genome is used in the cis test made from the two single mutant genomes used in the trans test by recombination. If the wild type phenotype is restored by both cis and trans arrangements it is concluded that the two mutations are in different genes and hence that the phenotype is determined by more than one gene. If the trans test is negative and the cis positive this means that the two mutations are in the same gene. If both tests are negative then at least one of the mutations must be dominant. Thus the double test provides a means of fine mapping of genes. A lab test which is used to determine whether two mutations of different genes which affect the same phenotype are on the same functional unit (indicating a cis configuration of the mutated genes) or on different functional units (indicating a trans configuration of the mutated genes). (A functional unit can be a chromosome.) The test is done by mating an individual that has one of the mutations to an individual that has the other one, and observing whether their offspring have the mutant phenotype. If the offspring do not have the mutant phenotype, then the genes are known to be trans, because the offspring have normal copies of each mutant gene on the different functional units which are able to genetically complement each other. If the offspring do have the mutant phenotype, then the genes are known to be cis, because the offspring will always inherit at least one of the mutant genes on the one functional unit, resulting in the mutant phenotype. (09 Oct 1997) |
| cis- | 1. <prefix> Prefix meaning on this side, on the near side; opposite of trans-. 2. <genetics> A prefix denoting the location of two or more genes on the same chromosome of a homologous pair, in coupling. 3. <chemistry> A form of geometric isomerism in which similar functional groups are attached on the same side of the plane that includes two adjacent, fixed carbon atoms (e.g., the 2-and 3-OH groups of ribofuranose) in a ring structure. Identical functional groups on the same side of the double bond are cis-. When the four moieties attached to the carbons of the double bond are all different, then the E/Z nomenclature has to be followed. See: entgegen, zusammen. Origin: L. (20 Jun 2000) |
| cis-1,2-dihydrobenzene-1,2-diol dehydrogenase | <enzyme> See also EC 1.3.1.20 (trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; both enzymes catalyze the conversion of benzene dihydrodiol to catechol and may also have hydroxysteroid dehydrogenase activity Chemical name: cis-1,2-dihydroxycyclohexa-3,5-diene (nad) oxidoreductase Registry number: EC 1.3.1.19 Synonym: cis-benzene glycol dehydrogenase, cis-diol dehydrogenase, benzene dihydrodiol dehydrogenase, bedd gene product, nad+-dependent cis-benzene dihydrodiol dehydrogenase, todd gene product (26 Jun 1999) |
| cis-3-chloroacrylic acid dehalogenase | <enzyme> Specific for conversion of cis-3-chloroacrylic acid to muconic saemialdehyde (3-oxopropionic acid); 48 amino-terminal amino acid sequence given in first source Registry number: EC 3.8.1.- Synonym: cis-3caa dehalogenase (26 Jun 1999) |
| cis-9,trans-11-octadecadienoate reductase | <enzyme> Uses NADH and alpha-tocopherol quinol; forms trans-11-octadecenoate Registry number: EC 1.3.1.- Synonym: 9,11-ocdd reductase (26 Jun 1999) |
| cis-aconitic acid | Dehydration product of citric acid; an enzyme-bound intermediate in the tricarboxylic acid cycle. (05 Mar 2000) |
| cis-acting locus | A section of DNA that affects the activity of DNA sequences on that same molecule of DNA. (05 Mar 2000) |
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| CI | function of an angle expressed as a ratio of the sides of right-angled triangle containing the angle |
|---|---|
| CI | measurement of angles in radians |
| CI | a plane with a flexible face that can plane concave or convex surfaces |
| CI | a power saw that has a steel disk with cutting teeth on the periphery |
| CI | knitted in tubular form |
| CI | circulating printed notices as a means of advertising |
| CI | cause to become widely known |
| CI | distribute circulars to |
| CI | canvass by distributing letters |
| CI | the roundness of a 2-dimensional figure |
| CI | circulating printed notices as a means of advertising |
| CI | make circular |
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