| amination | The creation of an amine, either by addition of an amino group to an organic acceptor compound or by reduction of a nitro compound. (12 Dec 1998) |
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| amine | <biochemistry> An organic compound containing nitrogen, any member of a group of chemical compounds formed from ammonia by replacement of one or more of the hydrogen atoms by organic (hydrocarbon) radicals. The amines are distinguished as primary, secondary and tertiary, according to whether one, two or three hydrogen atoms are replaced. The amines include allylamine, amylamine, ethylamine, methylamine, phenylamine, propylamine and many other compounds. (18 Nov 1997) |
| amine oxidase | <enzyme> A group of enzymes including those oxidizing primary monoamines, diamines, and histamine. They are copper proteins, and, as their action depends on a carbonyl group, they are sensitive to inhibition by saemicarbazide. Chemical name: Amine:oxygen oxidoreductase (deaminating)(copper-containing) Registry number: EC 1.4.3.6 (12 Dec 1998) |
| amine oxidase (copper-containing) | An oxidoreductase containing copper, and perhaps pyridoxal phosphate, and carrying out the same reaction as amine oxidase (flavin-containing). Synonym: amine oxidase (pyridoxal-containing), diamine oxidase, diamino oxyhydrase, histaminase. (05 Mar 2000) |
| amine oxidase (flavin-containing) | An oxidoreductase containing flavin and oxidizing amines with the aid of O2 and water to aldehydes or ketones with the release of NH3 and H2O2. Acted upon by antidepressants. Synonym: adrenaline oxidase, diamine oxidase, monoamine oxidase, tyraminase, tyramine oxidase. (05 Mar 2000) |
| amine oxidase (pyridoxal-containing) | amine oxidase (copper-containing) |
| amine oxidoreductases | <enzyme> Enzymes catalyzing the dehydrogenation of secondary amines, introducing a c=n double bond as the primary reaction. In some cases this is later hydrolyzed. Registry number: EC 1.5. (12 Dec 1998) |
| Amine Precursor Uptake and Decarboxylation | <pharmacology, physiology> Paracrine cells of which argentaffin cells are an example. Usage of the term APUD is neither helpful nor memorable. Acronym: APUD (11 Nov 1997) |
| amine sulfotransferase | <enzyme> Catalyses reversibly the reaction of 3'-phosphoadenylylsulfate and an arylamine to yield adenosine 3',5'-bisphosphate and an arylsulfamate Registry number: EC 2.8.2.3 Synonym: aniline sulfotransferase, arylamine sulfotransferase (26 Jun 1999) |
| amine tetrazolium reductase | <enzyme> Tetrazolium salts as hydrogen acceptors Registry number: EC 1.4.- Synonym: tryptamine dehydrogenase, monoamine tetrazolium reductase, monoamine dehydrogenase (26 Jun 1999) |
| aminergic | Relating to nerve cells or fibres. (05 Mar 2000) |
| amines | A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (12 Dec 1998) |
| amino acid | <biochemistry> A class of organic molecules that containing an amino group and can combine in linear arrays to form proteins in living organisms. There are twenty common amino acids: alanine, arginine, aspargine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, and valine. They are key components in all living things from which proteins are synthesised by formation of peptide bonds during ribosomal translation of messenger RNA. All the amino acids have the L configuration, except glycine which is not optically active. Other amino acids occurring in proteins, such as hydroxyproline in collagen, are formed by post translational enzymatic modification of amino acid residues in polypeptide chains. There are also several important amino acids, such as the neurotransmitter y aminobutyric acid, that have no relation to proteins. Amino acids can now be produced by biotechnology in bulk using fermentation and biotransformation. Acronym: AA (13 Nov 1997) |
| amino acid activating enzyme | <enzyme> Enzymes catalyzing the formation of a specific aminoacyl-tRNA from an amino acid and adenosine 5'-triphosphate with the concomitant formation of adenosine 5'-monophosphate and pyrophosphate. Synonym: amino acid activating enzyme, aminoacyl-tRNA ligases. (05 Mar 2000) |
| amino acid activation | The first step of protein synthesis, whereby an amino acid reacts with adenosine triphosphate in the presence of aminoacyl RNA synthetase to produce an amino acid adenylate, which provides the energy necessary for the attachment of the amino acid to a specific transfer RNA molecule. (12 Dec 1998) |