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signal a. a method for minimizing noise interference in a periodic signal; the relative constancy of the signal intensity over time versus the randomness of noise is exploited by averaging the waveforms over a number of periods.
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signal n. an enlarged supraclavicular lymph node that is often the first sign of an abdominal tumor; called also sentinel n., Troisier's n., ganglion, or sign, and Virchow's n. or gland.
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signal p. signal sequence.
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signal s. a sequence of 15 to 30 amino acids occurring at the N-terminal of the precursors of secretory proteins; it is required for transport of the protein across the membrane of the rough endoplasmic reticulum into the cisternae, where it is immediately cleaved off by an endopeptidase. Called also leader s. and signal peptide.
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signal t. the process by which a cell receives and acts on some external chemical or physical signal, such as a hormone, including receiving the information at specific receptors in the plasma membrane, conveying the signal across the plasma membrane into the cell, and subsequently inducing an intracellular chain of other signalling molecules, thereby stimulating a specific cellular response.
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