von Economo's disease | A unique encephalitis, presumably viral in origin, which followed the influenza pandemic of 1914-1918. Symptoms included ophthalmoplegia and marked somnolence, and in many survivors, the delayed development of Parkinson's disease; the basis for postencephalitic Parkinsonism. Synonym: encephalitis lethargica, polioencephalitis infectiva. (05 Mar 2000) |
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Von Gierke's disease | <disease> A congenital disease caused by a metabolic error in which the body deposits an abnormally high amount of glycogen in the kidneys and liver, the disease produces symptoms such as hypoglycaemia (low blood sugar) and hyperlipaemia (an excess of lipid molecules in the blood, which can lead to problems such as clogged arteries and heart attacks). (09 Oct 1997) |
von hippel-lindau disease | <disease> A congenital disease characterised by the development of blood vesse ltumours in the retina of the eye and in the brain, lesions and cysts canalso develop in the spina lcord, pancreas, kidneys, and other organs. (09 Oct 1997) |
pelvic imflammatory disease | <disease> The inflammation of any of the female pelvic organs, usually due to infection from a sexually transmitted disease. PID can result in sterility if left untreated. (09 Oct 1997) |
pelvic inflammatory disease | <disease> An inflammatory process that results from other pelvic diseases, may result from gonorrhoea, chlamydia, ovarian cystic disease or postpartum infections. (27 Sep 1997) |
von Meyenburg's disease | A degenerative disease of cartilage producing a bizarre form of arthritis, with collapse of the ears, the cartilaginous portion of the nose, and the tracheobronchial tree; death may occur from chronic infection or suffocation because of loss of stability in the tracheobronchial tree of autosomal origin. Synonym: chronic atrophic polychondritis, generalised chondromalacia, Meyenburg's disease, Meyenburg-Altherr-Uehlinger syndrome, relapsing perichondritis, systemic chondromalacia, von Meyenburg's disease. (05 Mar 2000) |
von Recklinghausen disease | type 1 neurofibromatosis |
von Recklinghausen's disease | <disease> A rare genetic disorder which affects the cell growth of nerve tissue. Individuals have multiple cutaneous and subcutaneous tumours which appear in late childhood. Clinical features include medium-brown, flat discolourations to the skin, known as cafe-au-lait spots. Secondary hypertension may develop from renal artery stenosis, pheochromocytoma or coarctation of the aorta. Inheritance: autosomal dominant. (04 Nov 1997) |
Von Willebrand disease | <disease, haematology> A hereditary platelet disorder caused by defective or deficient Von Willebrand factor, a protein involved in normal blood clotting, that reduces adhesion to collagen but not aggregation. Both bleeding time and coagulation are increased. Factor VIII levels are secondarily reduced. Symptoms include nosebleeds, bleeding gums, heavy menstrual bleeding, bruising and skin rashes. Inheritance: autosomal dominant. (30 Sep 1997) |
Von Willebrand's disease | <disease> This congenital disease, which is caused a deficiency of a blood factor that promotes platelet adhesion, is characterised by prolonged bleeding and poor blood coagulation. (09 Oct 1997) |
Voorhoeve's disease | Linear striations seen radiographically in the metaphyses of long bones and also flat bones; it may be a variant of osteopoikilosis. Synonym: Voorhoeve's disease. (05 Mar 2000) |
Meige's disease | Autosomal dominant lymphedema with onset at about the age of puberty. (05 Mar 2000) |
cerebrovascular disease | <cardiology, pathology> A general term which encompasses a variety of diseases which affect (via the occlusive effects of atherosclerosis) the arteries which supply the brain. See: stroke. (12 Jan 1998) |
retinal disease | <ophthalmology> A general term which describes any retinal changes (haemorrhages or exudates) that can affect vision (for example diabetic retinopathy, hypertensive retinopathy). (27 Sep 1997) |
Goldflam disease | <disease, neurology> The characteristic feature of the disease is easy fatigue of certain voluntary muscle groups on repeated use. Muscles of the face or upper trunk are especially likely to be affected. In most and perhaps all cases due to the development of autoantibodies against the acetylcholine receptor in neuromuscular junctions. Immunisation of mice or rats with this receptor protein leads to a disease with the features of myasthenia. (18 Nov 1997) |
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