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estrogen r. a type of nuclear receptor consisting of a cellular regulatory protein that binds estrogens, found on nearly all cell types, but particularly in estrogen-sensitive tissues such as the uterus and breast. Cytoplasmic levels are measured in surgically removed breast carcinoma; high levels indicate that a positive response to endocrine therapy is likely.
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estrogen replacement t. administration of an estrogen to treat estrogen deficiency, such as that following menopause; indications include the prevention of postmenopausal osteoporosis and coronary artery disease. In women with a uterus, a progestational agent is usually included to prevent endometrial hyperplasia. Called also hormone replacement t.
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estrogenic h. estrogen.
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estrogenicity the quality of exerting or the ability to exert an estrus-producing or an estrogenic effect.
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estrogenous estrogenic.
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