| adenylylosuccinate lyase | <enzyme> An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyses the conversion of 5'-phosphoribosyl-4-(n-succinocarboxamide)-5-aminoimidazole to 5'-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. Chemical name: N(6)-(1,2-Dicarboxyethyl)AMP AMP-lyase Registry number: EC 4.3.2.2 (12 Dec 1998) |
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| adenylylosuccinate synthase | <enzyme> A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyses the synthesis of adenylosuccinate from GTP, imp, and aspartate with the formation of orthophosphate and GDP. Chemical name: IMP:L-aspartate ligase (GDP-forming) Registry number: EC 6.3.4.4 (12 Dec 1998) |
| adenylylosuccinic acid | A condensation product of aspartic acid and inosine 5'-monophosphate; an intermediate in the biosynthesis of adenylic acid. Formally, it is adenylic acid with succinic acid replacing an H of the NH2 group, forming a C-N. Synonym: adenylylosuccinic acid, N-succinyladenylic acid. Acronym: sAMP (05 Mar 2000) |
| adenylylsulfate kinase | adenosine 5'-phosphosulfate kinase |
| adeps | 1. Denoting fat or adipose tissue. 2. The rendered fat of swine, lard, used in the preparation of ointments. Synonym: lard. See: adeps lanae. Origin: L. Lard, fat (05 Mar 2000) |
| adeps lanae | The greasy substance obtained from the wool of the sheep Ovis aries (family Bovidae). Used as an emollient base for creams and ointments. Synonym: hydrous wool fat, lanolin, wool wax. Origin: L. Fat of wool (05 Mar 2000) |
| adeps renis | An obsolete term for the layer of adipose tissue ("fatty capsule") surrounding the kidney (perirenal fat). (05 Mar 2000) |
| ADEPT | <pharmacology> A method for targeting a drug to a specific tissue, in which the targeting agent and the drug are administered separately. The drug is designed to be inactive (a prodrug) until it is converted by an enzyme, which is the targeting agent. The enzyme is coupled to an antibody that directs it to the tissue of interest. When the enzyme arrives at the tissue, the prodrug is activated only at that site, sparing other tissues from potentially toxic side effects. Acronym: ADEPT (14 Nov 1997) |
| adeptist | A skilled alchemist. Source: Websters Dictionary (01 Mar 1998) |
| adequal cleavage | Cleavage resulting in the formation of blastomeres of approximately equal size. (05 Mar 2000) |
| adequate | Satisfactory in quantity or quality, sufficient. (18 Nov 1997) |
| adequate stimulus | A stimulus to which a particular receptor responds effectively and that gives rise to a characteristic sensation; e.g., light and sound waves that stimulate, respectively, visual and auditory receptors. (05 Mar 2000) |
| adequation | The act of equalizing; act or result of making adequate; an equivalent. Origin: L. Adaequatio. Source: Websters Dictionary (01 Mar 1998) |
| adermia | Congenital defect or absence of skin. Origin: G. A-priv. + derma, skin (05 Mar 2000) |
| adermogenesis | Failure or imperfection in the regeneration of the skin, especially the imperfect repair of a cutaneous defect. Origin: G. A-priv. + derma, skin, + genesis, origin (05 Mar 2000) |