| SA | salicylic acid; saline [solution]; salt added; sarcoidosis; sarcoma; scalenus anticus; secondary ame... |
|---|---|
| CIA | chemiluminescent immunoassay; chymotrypsin inhibitor activity; colony-inhibiting activity; congenita... |
| ECA | electrical control activity; electrocardioanalyzer; endothelial cytotoxic activity; enterobacterial ... |
| FA | false aneurysm; Families Anonymous; Fanconi anemia; far advanced; fatty acid; febrile antigen; femor... |
| IA | ibotenic acid; immune adherence; immunoadsorbent; immunobiologic activity; impedance angle; indolami... |
| structure activity analysis | Study in which systematic variation in the structure of a compound is correlated with its activity, in an attempt to determine the characteristics of the (receptor) site at which it acts. (18 Nov 1997) |
|---|---|
| structure-activity relationship | The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Other factors contributing to structure-activity relationship include chemical reactivity, electronic effects, resonance, and inductive effects. (12 Dec 1998) |
| nonsuppressible insulin-like activity | A blood protein (nsila) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of cohn fraction III, 10% of the activity is found in the supernatant (nsila-s) and the remaining activity in the precipitate (nsila-p). The latter is a large molecular compound, much less stable than the soluble fraction. Nsila-s is a more potent growth factor than insulin and exhibits sulfation activity. (12 Dec 1998) |
| drug activity | A measure of the physiological response a drug produces. A less active drug produces less response (and visa versa). (12 Dec 1998) |
| insulin-like activity | A measure of substances, usually in plasma, that exert biologic effects similar to those of insulin in various bioassays; sometimes used as a measure of plasma insulin concentrations; always gives higher values than immunochemical techniques for the measurement of insulin. (05 Mar 2000) |
| intrinsic sympathomimetic activity | The property of a drug that causes activation of adrenergic receptors so as to produce effects similar to stimulation of the sympathetic nervous system. (05 Mar 2000) |
| optical activity | The ability of a material to rotate the plane of polarized light. (09 Oct 1997) |
| triggered activity | One or a series of spontaneously generated heart beats originating from an action potential that produces an after-depolarisation which reaches activation threshold. (05 Mar 2000) |
| unit of thyrotrophic activity | The activity of an amount of an extract of the anterior lobe of the hypophysis which, given daily for 5 days, will cause the thyroid of a guinea pig (weighing 200 g) to reach a weight of 600 mg. (05 Mar 2000) |
| androgenic zone | A transient adrenocortical zone present in some rodents at birth, most notably in mice, situated between the zona reticularis and the adrenal medulla; it degenerates in males with the secretion at puberty and in females during their first pregnancy; it slowly enlarges in unmated females after puberty and does not degenerate until middle age; the X zone appears to secrete no hormone. Synonym: androgenic zone. Misnomer for the foetal adrenal cortex of primates. Synonym: foetal reticularis. (05 Mar 2000) |
| arcuate zone | The inner third of the basilar membrane of the cochlear duct extending from the tympanic lip of the osseous spiral lamina to the outer pillar cell of the spiral organ (of Corti). Synonym: zona arcuata, zona tecta. (05 Mar 2000) |
| Barnes' zone | The lower fourth of the pregnant uterus, attachment of the placenta to any part of which may cause dangerous haemorrhage. Synonym: cervical zone. (05 Mar 2000) |
| buffer zone | <ecology> An area of land separating two distinct land uses that acts to soften or mitigate the effects of one land use on the other. (09 Oct 1997) |
| capillary zone electrophoresis | A method for separating molecules extremely rapidly based on their electrophoretic mobility. (05 Mar 2000) |
| vascular zone | An area in the external acoustic meatus where a number of minute blood vessels enter from the mastoid bone. Synonym: spongy spot, zona vasculosa. (05 Mar 2000) |