| 영문 | hormone | 한글 | 호르몬 |
|---|---|---|---|
| 설명 | 호르몬이란 특정한 내분비선에서 생성, 저장되어 있다가, 관류하는 혈액 중으로 분비된 다음 혈액에 실려 멀리 떨어져 있는 표적세포(호르몬이 작용을 나타내는 세포)에 이르러 그곳에서 특정한 기능을 발휘하는 물질을 말한다. 내분비샘이 아니더라도 어느 세포나 세포군에서 세포외액 중으로 분비된 다음 다른 세포에 가서 세포의 기능을 변동시키는 물질의 일부도 호르몬의 범주에 포함시키고 있으며 이들을 특별히 국소호르몬이라 부른다(예-아세틸콜린, 아드레날린, 콜레시스토키닌 등). 이에 비해서 특정 내분비샘에서 혈중으로 분비되는 진정한 의미의 호르몬들을 일반호르몬이라고 부른다. 호르몬을 흔히 3종의 무리로 분류를 하는데 아드레날린이나 thyroxine과 같이 아미노산의 유도체로 된 호르몬들(amine derivative), 많은 아미노산을 재료로 만들어졌거나 당단백으로 된 단백호르몬(peptide hormone), 그리고 콜레스테롤을 재료로 만들어진 지방호르몬(steroid hormone) 등으로 구분되며 이들은 대체로 종류에 따라 작용메커니즘을 달리하고 있다. |
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| 영문 | luteinizing hormone(LH) | 한글 | 황체형성호르몬 |
|---|---|---|---|
| 설명 | 여성의 월경은 정해진 순서에 의해 일어나게 된다. 먼저 난포자극호르몬이 뇌에서 분비되어 여성의 난소를 자극하게 되면 난포가 자극받아 난포호르몬(에스트로젠)을 분비하게 되고 이것은 다시 되먹이기 메커니즘 의해 뇌에 작용을 하여 황체화호르몬이 뇌에서 분비되고 이것이 이른바 절정에 이르렀을 때, 난포에서 배란이 일어나게 된다. 이후 난포는 황체로 변하게 되며, 배란된 난자가 수정되지 아니하면, 황체는 황체호르몬(프로게스테론)을 분비한 뒤 퇴화되고 곧 이어 월경이 일어나게 된다. 이 일은 정상적인 대부분의 여성에서 28일을 주기로 일어나며, 대개 황체화호르몬 절정 이후 마지막은 14일로 일정하다고 한다. |
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| DBP | diastolic blood pressure; dibutylphthalate; distobuccopulpal; Dohle body panmyelopathy; vitamin D-bi... |
|---|---|
| HVDRR | hypocalcemic vitamin D-resistant rickets |
| PIVKA | protein induced by vitamin K absence or antagonism |
| UBBC | unsaturated vitamin B12 binding capacity |
| VAD | venous access device; ventricular assist device; vinblastine and dexamethasone; vitamin A deficiency... |
| vitamin A | <biochemistry> Deficiency of this vitamin interferes with the production of rhodopsin in the eye resulting in night blindness and xerophthalmia. (27 Sep 1997) |
|---|---|
| vitamin A1 | Vitamin A1alcohol; 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene;a half-carotene bearing the b (or beta-ionone) form of the cyclic end group and a CH2OH at the C-15 position (numbering as in carotenoids) or 9'-position (numbering as a nonyl side chain on a cyclohexene ring); an intermediate in the vision cycle, it also plays a role in growth and differentiation. See: dehydroretinol. Synonym: vitamin A1 alcohol, vitamin A1. Retinol dehydrogenase, an oxidoreductase catalyzing interconversion of retinal and NADH to retinol and NAD+. (05 Mar 2000) |
| vitamin A1 acid | <biochemistry> The aldehyde (retinal) has long been known to be involved in photoreception, but retinoic acid has other roles. There are cytoplasmic retinoic acid binding proteins and retinoic acid response elements that regulate gene transcription. Retinoic acid is thought to be a morphogen in chick limb bud development and in early development of the chick that probably accounts for its potent teratogenic action. Synonym: vitamin A. (03 Jul 1999) |
| vitamin A1 alcohol | Vitamin A1alcohol; 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene;a half-carotene bearing the b (or beta-ionone) form of the cyclic end group and a CH2OH at the C-15 position (numbering as in carotenoids) or 9'-position (numbering as a nonyl side chain on a cyclohexene ring); an intermediate in the vision cycle, it also plays a role in growth and differentiation. See: dehydroretinol. Synonym: vitamin A1 alcohol, vitamin A1. Retinol dehydrogenase, an oxidoreductase catalyzing interconversion of retinal and NADH to retinol and NAD+. (05 Mar 2000) |
| vitamin A2 | 3-Dehydroretinol;retinol with an additional double bond in the 3-4 position of the cyclohexane ring. Synonym: vitamin A2. (05 Mar 2000) |
| vitamin A2 aldehyde | 3-Dehydroretinaldehyde;dehydroretinol with -CHO instead of -CH2OH at the terminal carbon of the side chain. Synonym: retinene-2, vitamin A2 aldehyde. (05 Mar 2000) |
| vitamin A aldehyde | <chemical> A carotenoid constituent of visual pigments. It is the oxidised form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration. Chemical name: Retinal (03 Jul 1999) |
| vitamin a deficiency | A nutritional condition produced by a deficiency of vitamin a in the diet, characterised by night blindness and other ocular manifestations such as dryness of the conjunctiva and later of the cornea (xerophthalmia). Vitamin a deficiency is a very common problem worldwide, particularly in developing countries as a consequence of famine or shortages of vitamin a-rich foods. In the united states it is found among the urban poor, the elderly, alcoholics, and patients with malabsorption. (12 Dec 1998) |
| vitamin A unit | The specific biologic activity of 0.3 ug of vitamin A (alcohol form). See: Sherman-Munsell unit. (05 Mar 2000) |
| vitamin B | A group of water-soluble substances originally considered as one vitamin. (05 Mar 2000) |
| vitamin B1 | <biochemistry> A member of the water-soluble B vitamin group, necessary for energy production and carbohydrate metabolism. Deficiency is known as beriberi. (27 Sep 1997) |
| vitamin B12 | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
| vitamin b 12 | <chemical> A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin b 12 from the soil and so are a poor source of the substance as compared with animal tissues. Pharmacological action: haematinics. Chemical name: Vitamin B12 (12 Dec 1998) |
| vitamin B12 absorption test | <investigation> This test measures the amount of vitamin B12 in the urine after ingesting a dose of B12. This test evaluates vitamin B12 absorption. The cells in the stomach produce a substance known as intrinsic factor. This substance combines with B12 to allow absorption in the distal ileum. The patient is given a small dose of radioactive B12 which can then be detected in the patients urine. Pernicious anaemia is the clinical result of B12 deficiency. Conditions that can result in an abnormal Schilling test include: deficiency of intrinsic factor, malabsorption or the development of an antibody to intrinsic factor. The Schilling test can be performed with or without administration of intrinsic factor to determine what the underlying cause for pernicious anaemia. Laxative use, renal insufficiency and hypothyroidism can all interfere with the results of this test. (27 Sep 1997) |
| vitamin B12 deficiency | A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). (27 Sep 1997) |