| PVR | peripheral vascular resistance; perspective volume rendering; poliovirus receptor; postvoiding resid... |
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| RVR | reduced vascular response; renal vascular resistance; repetitive ventricular response; resistance to... |
| SVR | sequential vascular response; systemic vascular resistance |
| TPVR | total peripheral vascular resistance; total pulmonary vascular resistance |
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| signal recognition particle receptor | Receptor for the signal recognition particle (SRP) found in the membrane of the endoplasmic reticulum. Also called docking protein. Heterodimeric, both protomers having GTP binding capacity, though dissimilar binding sites. Not until the complex of SRP, ribosome, message and nascent polypeptide chain binds to the SRP receptor is the block to further chain elongation released and concurrently the SRP is released, leaving the ribosome attached to the endoplasmic reticulum membrane. Cotranslational transport of the polypeptide delivers it into the lumen of the ER. (18 Nov 1997) |
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| signal response coupling | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
| signal sequence | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal-to-noise ratio | <microscopy> Also sometimes used as an abbreviation for serial number, can be somewhat confusing in the case of electronic equipment. (05 Aug 1998) |
| signal transduction | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
| nuclear localization signal | Short, predominantly basic amino acid sequences identified as nuclear import signals for some proteins. These sequences are believed to interact with specific receptors at nuclear pores. (12 Dec 1998) |
| acute vascular occlusion | <cardiology, surgery> A serious condition that results from the sudden blockage of an artery, usually with a blood clot. (27 Sep 1997) |
| acute vascular purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| articular vascular circle | An anastomosis of vessels encircling a joint. See: articular vascular network. Synonym: circulus articularis vasculosus. (05 Mar 2000) |
| articular vascular network | A vascular rete in the neighborhood of a joint, where such arrangements are common, enabling a collateral circulation by which blood will be supplied distal to the joint regardless of compromises resulting from joint position. Synonym: circulus articularis vasculosus, rete vasculosum articulare, articular network. (05 Mar 2000) |
| articular vascular network of elbow | Vascular networks in the region of the elbow, composed of anastomoses between branches of the radial and middle collateral, superior and inferior ulnar collateral, radial recurrent, interosseous recurrent, and recurrent ulnar arteries. Synonym: rete articulare cubiti. (05 Mar 2000) |
| articular vascular network of knee | An arterial network over the front and sides of the knee, formed by branches of the descending genicular artery, of the five genicular arteries from the popliteal, of the anterior tibial recurrent, and of the fibular circumflex branch of the posterior tibial. Synonym: rete articulare genus. (05 Mar 2000) |
| atherosclerotic vascular disease | <cardiology> The progressive narrowing and hardening of the arteries over time. This is known to occur to some degree with aging, but other risk factors that accelerate this process have been identified. These factors include: high cholesterol, high blood pressure, smoking, diabetes and family history for atherosclerotic disease. (27 Sep 1997) |
| blood-vascular system | The heart and the blood vessels by which blood is pumped and circulated through the body. (12 Dec 1998) |
| vascular | <physiology> Pertaining to blood vessels or indicative of a copious blood supply. (18 Nov 1997) |