| tosylphenylalanyl chloromethyl ketone | <chemical> An inhibitor of serine proteinases. Acts as alkylating agent and is known to interfere with the translation process. Pharmacological action: alkylating agents, protein synthesis inhibitor, serine proteinase inhibitors. Chemical name: Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)- (12 Dec 1998) |
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| ketone | <biochemistry> A byproduct of fat metabolism. An overabundance of ketones in the bloodstream is seen in a severe metabolic derangement known as diabetic ketoacidosis. (27 Sep 1997) |
| ketone alcohol | A compound containing a carbonyl or ketone group as well as a hydroxyl group; e.g., dihydroxyacetone. (05 Mar 2000) |
| ketone-aldehyde mutase | <enzyme> An enzyme that catalyses the interconversion of methylglyoxal and lactate, with glutathione serving as a coenzyme. Chemical name: S-Lactoyl-glutathione methylglyoxal-lyase (isomerizing) Registry number: EC 4.4.1.5 (12 Dec 1998) |
| ketone bodies | The substances beta-hydroxybutyric acid, acetoacetic acid, and acetone, which are produced by fatty acid and carbohydrate metabolism in the liver in approximately a 78:20:2 ratio. Acetoacetate is produced from acetyl-CoA. most is enzymatically converted to beta-ketobutyrate, but a small amount is spontaneously decarboxylated to acetone. The ketone bodies can be used as fuels by muscle and brain tissue. In starvation and uncontrolled diabetes mellitus, large quantities are produced, causing metabolic acidosis and elevated blood and urine levels of all three ketone bodies. (12 Dec 1998) |
| ketone body | <biochemistry> Any of the three compounds created by acetyl coenzyme A (acetoacetate, hydroxybutyrate, and acetone) which are water-soluble cellular fuels normally exported by the liver. They can build up in the blood and body tissues because of starvation, untreated diabetes mellitus, or other disorders that interfere with carbohydrate metabolism. The body rids itself of ketones mainly through urine, but it rids itself of acetone through the lungs, which gives the breath a characteristic fruity odour. If ketones build up in the body long enough, they cause serious illness and coma (see ketoacidosis.) (09 Oct 1997) |
| ketone oxidoreductases | <enzyme> Registry number: EC 1.2. (12 Dec 1998) |
| antibody-coated bacteria test, urinary | Fluorescent antibody technique for visualizing antibody-bacteria complexes in urine. The presence or absence of antibody-coated bacteria in urine correlates with localization of urinary tract infection in the kidney or bladder, respectively. (12 Dec 1998) |
| anti-infective agents, urinary | Substances capable of killing agents causing urinary tract infections or of preventing them from spreading. (12 Dec 1998) |
| apex of urinary bladder | The junction of the superior and anteroinferior surfaces of the bladder, continuous above with the median umbilical ligament. Synonym: apex vesicae. (05 Mar 2000) |
| blood, urinary | Medically called haematuria, blood in the urine can be microscopic or gross. Evaluating haematuria requires consideration of the entire urinary tract. Tests used for the diagnosis of haematuria include the intravenous pyelogram (IVP), cystoscopy, and urine cytology. Management of haematuria depends upon the underlying cause. (12 Dec 1998) |
| body of urinary bladder | The portion of the bladder between the apex and fundus. Synonym: corpus vesicae urinariae. (05 Mar 2000) |
| reproductive and urinary physiology | Physiology of the human and animal body, male or female, in the reproductive process and the physiology of the urinary tract. (12 Dec 1998) |
| mucosa of urinary bladder | The inner coat of the urinary bladder. Synonym: tunica mucosa vesicae urinariae. (05 Mar 2000) |
| muscular coat of urinary bladder | Muscular layer of the wall of the urinary bladder. Synonym: tunica muscularis vesicae urinariae. (05 Mar 2000) |