| purpura, henoch-schonlein | HSP is a form of blood vessel inflammation, a vasculitis that affects small arterial vessels in the skin (capillaries) and the kidneys. Hsp results in skin rash associated with joint inflammation (arthritis) and cramping pain in the abdomen. Hsp frequently follows a bacterial or viral infection of the throat or breathing passages and is an unusual reaction of the body's immune system to this infection. Hsp occurs most commonly in children. Hsp is generally a mild illness that resolves spontaneously, but sometimes it can cause serious problems in the kidneys and bowels. Treatment is directed toward the most significant area of involvement. Joint pain can be relieved by antiinflammatory medications, such as aspirin or ibuprofen. Some patients can require cortisone-related medications, such as prednisone, especially those with significant abdominal pain or kidney disease. Also known as anaphylactoid purpura. (12 Dec 1998) |
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| purpura, hyperglobulinaemic | Purpura associated with an increase in gamma-globulins. The condition is no longer considered a specific entity since the clinical and laboratory findings are observed in a variety of haematologic conditions. (12 Dec 1998) |
| purpura iodica | Iodic purpura, an eruption of discrete miliary petechiae, usually confined to the lower extremities, appearing in rare instances on administration of any of the iodides. (05 Mar 2000) |
| purpura nervosa | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| purpura pulicans | Purpura pulicosa, petechiae caused by the bites of insects and animal parasites. (05 Mar 2000) |
| purpura rheumatica | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| purpura, schoenlein-henoch | A form of nonthrombocytopenic purpura due to a hypersensitivity vasculitis (vasculitis, hypersensitivity) associated with a variety of clinical symptoms including urticaria and erythema, arthropathy and arthritis, gastrointestinal symptoms, and renal involvement. (12 Dec 1998) |
| purpura senilis | The occurrence of petechiae and ecchymoses on the atrophic skin of the legs in aged and debilitated subjects. (05 Mar 2000) |
| purpura simplex | The eruption of petechiae or larger ecchymoses, usually unaccompanied by constitutional symptoms and not associated with systemic illness. Synonym: nonthrombocytopenic purpura. (05 Mar 2000) |
| purpura symptomatica | A petechial eruption in scarlet fever and other exanthemas. (05 Mar 2000) |
| purpura, thrombocytopenic | Any form of purpura in which the platelet count is decreased. Many forms are thought to be caused by immunological mechanisms. (12 Dec 1998) |
| purpura, thrombocytopenic, idiopathic | Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IgG autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms. (12 Dec 1998) |
| purpura, thrombotic thrombocytopenic | A disease characterised by thrombocytopenia, haemolytic anaemia, bizarre neurological manifestations, azotemia, fever, and thromboses in terminal arterioles and capillaries. (12 Dec 1998) |
| purpura urticans | Purpura simplex accompanied by an urticarial eruption. (05 Mar 2000) |
| hyperglobulinaemic purpura | <haematology> A condition characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate and hyperglobulinaemia. Physical findings include mucosal bleeding, skin purpura and enlargement of the lymph nodes, liver and spleen. Origin: Gr. Haima = blood (27 Sep 1997) |