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PEP protein tyrosine phosphatase <enzyme> Pest - pro, glu, ser and thr; an intracellular ptpase expressed primarily by cells of haematopoietic origin; involved in regulating nuclear tyrosine phosphorylation; amino acid sequence has been determined
Registry number: EC 3.1.3.-
Synonym: pep ptpase, pest-enriched phosphatase, ptp-pest
(26 Jun 1999)
RNA-tyrosine phosphatase <enzyme> Hela cell enzyme which removes 5'-terminal protein from poliovirus RNA by breaking the tyrosine-phosphate bond between the above two entities
Registry number: EC 3.1.4.-
Synonym: uridylyl-(5'p-o)-tyrosine phosphodiesterase, y-pupnpde, tyrosine-RNA phosphatase, uridylylpolynucleotide-(5'p-o)-tyrosine phosphodiesterase
(26 Jun 1999)
PL7a receptor-tyrosine kinase <enzyme> A member of the eph receptor tyrosine kinase subfamily; shows 80% identity with myk-1; genbank l43622
Registry number: EC 2.7.1.-
Synonym: pl7a protein
(26 Jun 1999)
H1-related protein-tyrosine phosphatase <enzyme> Has tyrosine and threonine/serine phosphatase activities
Registry number: EC 3.1.3.-
Synonym: vaccinia virus h1-related protein tyrosine phosphatase, vhr ptpase, vh-ptp13
(26 Jun 1999)
Csk-like protein-tyrosine kinase <enzyme> Phosphorylates c-terminal conserved tyr of src family members; from mouse brain; has 52% identity with mouse csk; mw 52 kD; genbank u05210
Registry number: EC 2.7.1.-
Synonym: ctk (kinase), ctk gene product, csk-type protein-tyrosine kinase, ntk (kinase), bhk (kinase)
(26 Jun 1999)
protein-tyrosine kinase <enzyme> An enzyme that catalyses the phosphorylation of tyrosine residues in proteins with ATP or other nucleotides as phosphate donors.12.
Chemical name: ATP:protein-tyrosine O-phosphotransferase
Registry number: EC 2.7.1.112
(12 Dec 1998)
protein-tyrosine-phosphatase <enzyme> An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with protein-tyrosine kinase, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
Chemical name: Protein-tyrosine-phosphate phosphohydrolase
Registry number: EC 3.1.3.48
(12 Dec 1998)
pyp2 protein tyrosine phosphatase <enzyme> Shares an essential overlapping role with pyp1 ptpase and is 42% identical in sequence in the c-terminal catalytic domain of pyp1; involved in negative regulation of mitosis in fission yeast
Registry number: EC 3.1.3.-
Synonym: pyp2 ptpase, pyp2 gene product
(26 Jun 1999)
pyp3 protein tyrosine phosphatase <enzyme> Acts as mitotic inducer in fission yeast
Registry number: EC 3.1.3.-
Synonym: pyp3 gene product, pyp3 ptpase
(26 Jun 1999)
SH protein-tyrosine phosphatase <enzyme> Has sequence similarity to src-homology region 2
Registry number: EC 3.1.3.-
Synonym: sh-ptp3, sh-ptp1, ptp1c, protein-tyrosine-phosphatase 1c, protein tyrosine phosphatase, nonreceptor type 6, ptpn6, shptp1, protein-tyrosine phosphatase shp, shp ptpase, shp-1, shp-2
(26 Jun 1999)
stomach cancer-associated protein-tyrosine phosphatase <enzyme> Human transmembrane-type ptpase expressed in gastric, pancreatic and colourectal cancer cells; consists of 1093 amino acid; mw 200 kD; genbank d15049
Registry number: EC 3.1.3.-
Synonym: sap 1 phosphatase
(26 Jun 1999)
nonreceptor protein tyrosine kinase <enzyme> Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single transmembrane domain and an intracellular tyrosine kinase domain and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases.
(18 Nov 1997)
NU-3 protein tyrosine phosphatase <enzyme> The murine homolog of rat cam tyrosine phosphatase; has an extracellular cell-adhesion-molecule-like domain; mw 211 kD; genbank x82288
Registry number: EC 3.1.3.-
Synonym: nu-3 ptp, ptp nu-3
(26 Jun 1999)
Dopa-tyrosine sulfotransferase <enzyme> Active towards tyrosine and dopa isomers except dl-ortho-tyrosine; isolated from rat liver; genbank u38419
Registry number: EC 2.8.2.-
(26 Jun 1999)
insulin receptor protein-tyrosine kinase <enzyme> A catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of the insulin receptor.
Registry number: EC 2.7.1.-
(12 Dec 1998)
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