| host restriction-modification | A bacterial system where the bacterium is able to destroy invading DNA from a bacteriophage (virus which infects bacteria) while at the same time preventing the destruction of their own DNA. The phage DNA is cleaved by a restriction enzyme made by the bacterium, the bacterial DNA is modified (usually with methylation) so that the enzyme will not destroy it. (09 Oct 1997) |
|---|---|
| host-vector system | A combination of a bacterial host cell (i.e. A specific strain) and a virus vector (i.e. A particular bacteriophage strain) which work well together for DNA cloning. (09 Oct 1997) |
| host versus graft reaction | The normal lymphocyte mediated reactions of a host against allogeneic or xenogeneic cells acquired as a graft or otherwise, which lead to damage or/and destruction of the grafted cells. The opposite of graft-versus-host reaction. The common basis of graft rejection. (18 Nov 1997) |
| host vs graft reaction | The immune responses of a host to a graft. A specific response is graft rejection. (12 Dec 1998) |
| dead-end host | A host from which infectious agents are not transmitted to other susceptible host's. (05 Mar 2000) |
| definitive host | <epidemiology> The host in which a parasite reproduces sexually. (05 Dec 1998) |
| disease, graft-versus-host | A reaction of donated bone marrow against a patient's own tissue. Also called GVHD. (12 Dec 1998) |
| immunocompromised host | A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation. (12 Dec 1998) |
| intermediate host | <epidemiology> See vector. (05 Dec 1998) |
| transport host | An intermediate host in which no development of the parasite occurs, although its presence may be required as an essential link in the completion of the parasite's life cycle; e.g., the successive fish host's that carry the plerocercoid of Diphyllobothrium latum, the broad fish tapeworm, to larger food fish eventually eaten by man or other final host's. Synonym: transport host. (05 Mar 2000) |
| final host | <epidemiology> The host in which a parasite reproduces sexually. (05 Dec 1998) |
| acrocephalosyndactyly type 1 | <paediatrics> An inherited disease (autosomal dominant) or a spontaneously occurring disease characterised by a peaked head and unusual facial appearance, due to the premature closure of the cranial sutures. A skull X-ray can confirm the diagnosis and treatment is surgical. Inheritance: autosomal dominant. (27 Sep 1997) |
| Alzheimer type I astrocyte | Enlarged frequently multinucleated astrocytes, seen in progressive multifocal leukoencephalopathy. (05 Mar 2000) |
| Alzheimer type II astrocyte | Enlarged astrocytes with vesicular nuclei and one or more small basophilic nucleoli, seen in hepatocerebral disease and Wilson's disease. (05 Mar 2000) |
| American Type Culture Collection | <cell culture> A key resource for cultured cells, located in Rockville, USA. (12 Dec 1998) |