| AP | accessory pathway; accounts payable; acid phosphatase; acinar parenchyma; action potential; active p... |
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| LPF | leukocytosis-promoting factor; leukopenia factor; lipopolysaccharide factor; localized plaque format... |
| PFC | pair-fed control [mice]; patient-focused care; pelvic flexion contracture; perfluorocarbon; pericard... |
| PFU | plaque-forming unit; pock-forming unit |
| PI | first meiotic prophase; isoelectric point; pacing impulse; package insert; pancreatic insufficiency;... |
| neuritic plaque | <cell biology> Abnormal cluster of dead and dying nerve cells, other brain cells and protein. Neuritic plaques are one of the characteristic structural abnormalities found in the brains of alzheimer patients. Upon autopsy, the presence of neuritic plaques andneurofibrillary tangles is used to positively diagnose Alzheimer's disease. (22 May 1997) |
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| dental plaque | <dentistry> A soft, thin film of food debris, mucin and dead epithelial cells deposited on the teeth, providing the medium for the growth of various bacteria. The main inorganic components are calcium and phosphorus with small amounts of magnesium, potassium and sodium, the organic matrix consists of polysaccharides, proteins, carbohydrates, lipids and other components. Plaque plays an important aetiological role in the development of dental caries and periodontal and gingival diseases and provides the base for the development of materia alba, calcified plaque forms dental calculus. (19 Mar 1998) |
| dental plaque index | An index which scores the degree of dental plaque accumulation. (12 Dec 1998) |
| fibrous plaque | Thickened area of arterial intima with accumulation of smooth muscle cells and fibrous tissue (collagen etc.) produced by the fat laden smooth muscle cells. Below the thickening may be free extracellular lipid and debris that, if much necrosis is also present, is referred to as an atheroma. (18 Nov 1997) |
| active mutant | A mutant with overt phenotypic expression. (05 Mar 2000) |
| amber mutant | A mutant with a mutation resulting in a UAG codon. (05 Mar 2000) |
| auxotrophic mutant | Mutant with a nutritional requirement not present in the wild type organism. Synonym: defective organism, deficiency mutant. (05 Mar 2000) |
| gap mutant | <molecular biology> A fruit fly of the genus Drosophila which is missing a number of adjacent segments because the segments failed to develop. (09 Oct 1997) |
| rats, mutant strains | Rats bearing mutant genes which are phenotypically expressed in the animals. (12 Dec 1998) |
| virulent phage mutant | A mutant of a phage that is unable to establish lysogeny. (05 Mar 2000) |
| relaxed mutant | A mutant bacterium that continues to synthesise RNA in a medium that lackscertain nutrients or amino acids which that sort of bacterium normallyneeds present before it can make RNA. (09 Oct 1997) |
| ced mutant | <organism> Giant multinucleate fresh water amoeba (up to 5mm long) much used for studies on the mechanism of cell locomotion. (18 Nov 1997) |
| cell division cycle mutant | A yeast cell which has cell division cycle genes that have mutated to become sensitive to temperature, at certain temperatures (usually high ones), various parts of the normal yeast cell cycle become abnormal, and in some strains the yeast cell does not survive at all. (09 Oct 1997) |
| petite mutant | <molecular biology, organism> A class of yeast mutants, most studied in Saccharomyces cerevisiae. Mutants grow slowly and rely on anaerobic respiration: mitochondria, although present, have reduced cristae and are functionally defective (termed promitochondria). There are three types of petite mutant: (i) Segregational mutants that show Mendelian behaviour and result from mutations in mitochondrial genes located in the nucleus. (ii) Neutral petites, which are recessive genotypes and result from the complete absence of mitochondrial DNA. (iii) Suppressive petites, in which most of the mitchondrial DNA is lost (60-99%), though what remains is often amplified. (06 Oct 1997) |
| mice, mutant strains | Mice bearing mutant genes which are phenotypically expressed in the animals. (12 Dec 1998) |