| tumor suppressor gene |
A gene that acts to prevent cell growth. If a mutation occurs in this gene, it may make the individual more susceptible to the development of cancer in the tissue in which the mutation occurs. This effect is a recessive effect in that each of the pair of genes must be abnormal for the tumor promoting action to occur.
출처: cll.ucsd.edu/glossaryt.htm
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| tumor suppressor gene |
A gene whose protein product is responsible for antiproliferative signals. The retinoblastoma gene product and the product of the p53 gene are two examples of tumor suppressor genes.
출처: www.jco.org/cgi/glossarylookup
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| tumor suppressor gene |
Gene that normally functions to inhibit cell growth and division cycles.
출처: www.mshri.on.ca/colorectalcancer/definitions.html
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| tumor suppressor gene |
genes that normally function to restrain the growth of tumors; the best understood case is for hereditary retinoblastoma.
출처: www.science.psu.edu/alert/frontiers/Glossary1-2001...
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| tumor suppressor gene |
A gene that acts to prevent a cell from becoming tumorigenic. The normal function of such genes is usually related to control of cell growth and/or division. Appropriate mutations to such a gene results in loss of control of such cell growth or division.
출처: www.mlamutations.com/glossary/glossary.html
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