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  • transformylation
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FHT fast Hartley transform; fetal heart; fetal heart tone
FT Fallot tetralogy; false transmitter; family therapy; fast twitch; fatigue trial; fibrous tissue; fin...
FTFT fast time frequency transform
STFT short-time Fourier transform
WT wall thickness; water temperature; wavelet transform; wild type [strain]; Wilms tumor; wisdom teeth;...
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DFT Discrete Fourier Transform
FFT Fast Fourie Transform
FT-IR Fourier Transform Infra Red
FT Fourier Transform
FTIR Fourier Transform Infra Red Spectroscopy
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transforming growth factor <growth factor> Proteins secreted by transformed cells that can stimulate growth of normal cells.
Unfortunate misnomer, since they induce aspects of transformed phenotype, such as growth in semi solid agar, but do not actually transform.
Transforming growth factor alpha, 50 amino acid polypeptide originally isolated from viral transformed rodent cells, contains EGF like domain and binds to EGF receptor. Stimulates growth of microvascular endothelial cells, i.e. Is angiogenic.
Transforming growth factor beta a homodimer of two 112 chains, polypeptide is secreted by many different cell types, stimulates wound healing but in vitro is also a growth inhibitor for certain cell types. The transforming growth factor family includes many of the bone morphogenetic proteins.
Acronym: TGF
(18 Nov 1997)
transforming growth factor alpha Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to epidermal growth factor (epidermal growth factor-urogasterone) and binds to the egf receptor. Tgf-alpha acts synergistically with tgf-beta in inducing phenotypic transformation, but its physiological role is unknown.
(12 Dec 1998)
transforming growth factor beta Factor synthesised in a wide variety of tissues including platelets, placenta, and both normal and transformed cell lines. It acts synergistically with tgf-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. Tgf-beta also has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. There are at least three forms of tgf-beta: tgf-beta1, tgf-beta2, and tgf-beta1.2. The latter is a heterodimer made up of both tgf-beta1 and tgf-beta2.
(12 Dec 1998)
transforming growth factors <chemical> Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumour-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, transforming growth factor alpha and transforming growth factor beta.
Chemical name: Animal growth regulators, transforming growth factors
(12 Dec 1998)
transforming oncogene <molecular biology> A gene that upon transfection converts a previously immortalised cell to the malignant phenotype.
(09 Oct 1997)
transforming virus <molecular biology, virology> Viruses capable of inducing malignant transformation of animal cells in culture. Among the Oncovirinae, nondefective viruses that lack oncogenes can induce tumours such as leukaemias in animals, but cannot transform in vitro. On acquisition of oncogenes they become (acute) transforming viruses.
(18 Nov 1997)
transformism <biology> The hypothesis, or doctrine, that living beings have originated by the modification of some other previously existing forms of living matter; opposed to abiogenesis.
Origin: F. Transformisme.
Source: Websters Dictionary
(01 Mar 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 3 ÆäÀÌÁö: 2
  • Transforming Growth Factor beta2 - »õâ A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
    Synonyms : BSC-1 Cell Growth Inhibitor, Cartilage-Inducing Factor-B, Glioblastoma-Derived T-Cell Suppressor Factor, Polyergin, Suppressor Factor, T-Cell, Glioblastoma-Derived, TGF-beta-2, TGF-beta2 Latency-Associated Protein, TGF-beta2LAP, BSC 1 Cell Growth Inhibitor
  • Transforming Growth Factor beta3 - »õâ A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
    Synonyms : TGF-beta-3, TGF-beta3 Latency-Associated Protein, TGF-beta3LAP, TGFB3, Transforming Growth Factor beta 3 Latency Associated Peptide, Latency-Associated Protein, TGF-beta3, TGF beta 3, TGF beta3, TGF beta3 Latency Associated Protein
  • Transforming Growth Factors - »õâ Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.
    Synonyms : Transforming Growth Factor, Factor, Transforming Growth, Factors, Transforming Growth, Growth Factor, Transforming, Growth Factors, Transforming
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transformer An allele in fruit flies (Drosophila) that converts chromosomal females into sterile males.
Ãâó: helios.bto.ed.ac.uk/bto/glossary/tuvwxyz.htm
transformation A process in which exogenous DNA is taken up by a (recipient) cell or protoplast, in which it may be incorporated into the chromosome (or, eg, into a plasmid) by homologous recombination or converted into an autonomous replicon. The DNA (transforming or donor DNA) may be a fragment of chromosomal DNA from a related strain, a plasmid, or a viral genome. (16)
Ãâó: ppathw3.cals.cornell.edu/glossary/Defs_T.htm
transformation a genetic change produced by the introduction of foreign DNA.
Ãâó: www.mycolog.com/GLOSSARY.htm
transformer A device used to transfer electric energy from one circuit to another.
Ãâó: www.reefed.edu.au/glossary/t.html
transformation Neoplastic transformation is the conversion of normal cells into tumour cells (see below). Frequently this is the result of a genetic change (mutagenesis) and the same term is used to describe the genetic modification of bacteria for use in biotechnology. See epigenetic changes, genetic toxicology, genotoxic, mutation, mutagenesis, tumour.
Ãâó: www.bio.hw.ac.uk/edintox/glossall.htm
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transform (mathematics) a function that changes the position or direction of the axes of a coordinate system
transform given a completely different form or appearance
transform an electrical device by which alternating current of one voltage is changed to another voltage
transform a gene that causes normal cells to change into cancerous tumor cells
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