| 영문 | iron deficiency anemia | 한글 | 철결핍빈혈 |
|---|---|---|---|
| 설명 | 적혈구의 기능은 산소를 운반하는데 있다. 적혈구 속에 산소와 결합을 하여 산소를 운반하는 혈색소라는 물질이 있다. 철은 이 혈색소의 중요한 부분을 이루는 것으로 철이 없으면 혈색소가 만들어질 수가 없다. 혈색소가 없으면 역시 적혈구도 만들어지지 않으므로 체내에 철이 부족하면 빈혈이 생긴다. 이 철결핍성 빈혈은 빈혈의 원인 중에서 가장 흔한 것이다(약 25%를 차지한다). 철저장량의 저하-결핍, 혈청철농도의 저하, 트란스페린량 상승, 트란스페린포화도의 저하, 혈색소농도 또는 헤마토크리트의 저하, 저색소성대적혈구를 특징으로 하는 빈혈로서, 생체 내에서 철이 장기에 걸쳐 결핍되며 그 때문에 혈색소 생산 감소에 의해 일어난다. 창자에서의 철흡수량 부족, 철의 수요 증대(유아기, 사춘기, 임신), 철소실과잉(출혈)에 의해 일어나며, 특히 사춘기에서 폐경기까지의 여성에게 많다. 증상으로서는 얼굴창백, 피로감, 피부창백, 손톱 변화(스푼 모양) 등을 나타낸다. 구강 영역에서는 혀의 접촉통, 발적, 건조감, 삼킴곤란을 수반하면 플러머-빈슨(Plummer-Vinson)증후군이라고 한다. 혈액 소견은 혈청철은 저하하며, 철결합능력의 상승, 저색소성 작은적혈구성을 나타낸다. |
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| toxic cirrhosis | Cirrhosis of the liver resulting from chronic poisoning, as by lead or carbon tetrachloride. (05 Mar 2000) |
|---|---|
| toxic cyanosis | Cyanosis due to methemoglobin formation resulting from the action of certain drugs, e.g., nitrites. (05 Mar 2000) |
| toxic delirium | Delirium caused by the action of a poison. (05 Mar 2000) |
| toxic effect | <physiology> The physiologic, physical or laboratory manifestations or derangement that can be attributed to the presence of a substance within the body. (12 Jan 1998) |
| toxic epidermal necrolysis | A syndrome in which a large portion of the skin becomes intensely erythematous with epidermal necrosis, and peels off in the manner of a second-degree burn, often simultaneous with the formation of flaccid bullae, resulting from drug sensitivity or of unknown cause; the level of separation is subepidermal, unlike staphylococcal scalded skin syndrome in which there is subcorneal change. Synonym: Lyell's syndrome. (05 Mar 2000) |
| toxic equivalent | The amount of toxin or other poison per kilogram of body weight necessary to kill an animal. (05 Mar 2000) |
| toxic goiter | A goiter that forms an excessive secretion, causing signs and symptoms of hyperthyroidism. (05 Mar 2000) |
| toxic haemoglobinuria | Haemoglobinuria occurring after the ingestion of various poisons, in certain blood diseases, and in certain infections. (05 Mar 2000) |
| toxic hydrocephalus | Thrombotic hydrocephalus associated with some general infection or toxic state. (05 Mar 2000) |
| toxic megacolon | <gastroenterology, surgery> An acute nonobstructive dilation of the colon, seen in advanced ulcerative colitis and Crohn's disease. (12 Jan 1998) |
| toxic multinodular goiter | Condition in which the thyroid gland contains multiple lumps (nodules) that are overactive, produce excess thyroid hormones and thereby cause hyperthyroidism. This condition is also known as parry's disease or plummer's disease. (12 Dec 1998) |
| toxic nephrosis | Acute oliguric renal failure due to chemical poisons, septicaemia, or bacterial toxaemia; frequently associated with extensive necrosis of proximal convoluted tubules. (05 Mar 2000) |
| toxic neuritis | Neuritis caused by an endogenous or exogenous toxin. (05 Mar 2000) |
| toxic nodular goitre | <endocrinology> An enlarged thyroid gland which contains nodules which release excess thyroid hormone. This condition usually arises from long-standing simple goitre in the elderly. Symptoms of hyperthyroidism result. (12 Jan 1998) |
| toxic psychosis | A psychosis caused by some toxic substance, whether endogenous or exogenous. (05 Mar 2000) |