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cholesterol, good High-density lipoprotein (HDL) cholesterol.
(12 Dec 1998)
cholesterol, hdl High-density lipoprotein cholesterol (the good cholesterol).
(12 Dec 1998)
cholesterol, ldl Low-density lipoprotein cholesterol (the bad cholesterol).
(12 Dec 1998)
cholesterol monooxygenase <enzyme> Multi-enzyme complex required for the conversion of cholesterol to adrenal cortex hormones. It releases methylpentanoate or isocaproaldehyde and pregnenolone. The complex contains cytochrome p-450, a flavoprotein, a non-haem iron protein, and NADPH.
Chemical name: Cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)
Registry number: EC 1.14.15.6
(12 Dec 1998)
cholesterol oxidase <enzyme> An enzyme that catalyses the oxidation of cholesterol in the presence of molecular oxygen to 4-cholesten-3-one and hydrogen peroxide. The enzyme is not specific for cholesterol, but will also oxidise other 3-hydroxysteroids.
Chemical name: Cholesterol:oxygen oxidoreductase
Registry number: EC 1.1.3.6
(12 Dec 1998)
cholesterol reductase <enzyme> Uses NADH; reduces cholesterol to cholestanol (coprostanol)
Registry number: EC 1.3.1.-
(26 Jun 1999)
cholesterol sulfotransferase <enzyme> Transfers sulfate from paps to cholesterol
Registry number: EC 2.8.2.-
(26 Jun 1999)
hdl cholesterol High-density lipoprotein cholesterol (the good cholesterol).
(12 Dec 1998)
high blood cholesterol A condition where there is an above normal level of cholesterol in the bloodstream. A level of over 200 mg/dl is known to be a risk factor for heart disease. Less than 200 is desirable, 200 to 239 is considered borderline high, over 240 is considered high.
(27 Sep 1997)
NAD(P)+-dependent cholesterol dehydrogenase <enzyme> Oxidises the 3 beta-oh group of cholesterol to cholestenone in the presence of NADP+
Registry number: EC 1.1.1.-
Synonym: NADP+-dc-dehydrogenase, cholesterol 3-dehydrogenase
(26 Jun 1999)
i-cholesterol isomerase <enzyme> 7-hydroxy group is isomerised to position 3 on ring a to form cholesterol
Registry number: EC 5.4.99.-
(26 Jun 1999)
embolism, cholesterol An embolism of lipid debris from an ulcerated atheromatous deposit, generally from a large artery to small arterial branches. It is usually small and rarely causes infarction.
(12 Dec 1998)
ldl cholesterol Low-density lipoprotein cholesterol (the bad cholesterol).
(12 Dec 1998)
lecithin-cholesterol acyltransferase <enzyme> An enzyme that reversibly transfers an acyl residue from a lecithin to cholesterol, forming a 1-acylglycerophosphocholine (a lysolecithin) and a cholesterol ester; a deficiency of this enzyme leads to an accumulation of unesterified cholesterol in plasma resulting in anaemia, proteinuria, renal failure, and corneal opacities; LCAT is also low in individuals with fish-eye disease.
Synonym: lecithin acyltransferase.
Acronym: LCAT
(05 Mar 2000)
lecithin-cholesterol transferase A plasma enzyme that catalyses the uptake of cholesterol esters by intermediate-density lipoproteins formed by high density lipoproteins.
(05 Mar 2000)
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