| 영문 | tissue | 한글 | 조직 |
|---|---|---|---|
| 설명 | 특정 구조와 기능을 갖는 세포 집단. 세포 사이에는 다소간 세포간질이 들어 있다. 세포간질에는 글리코사미노글리칸, 히드록시아파타이트와 같은 기질과 아교질섬유와 같은 섬유가 발견된다. 조직성상은 구성세포와 세포간질의 종류와 양에 의해 결정된다. 조직은 상피조직, 지지조직, 근육조직, 신경조직으로 대별되며, 상피조직은 세포간질을 거의 갖지 않으며, 지지조직은 결합조직이나 뼈조직과 같이 세포간질이 풍부한 것이 많다. |
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| 영문 | tissue biopsy | 한글 | 조직생검 |
|---|---|---|---|
| 설명 | 환자의 병적인 조직의 일부를 떼어 내서 병리조직표본을 만들어서 현미경적으로 검사하는 것. 외과적 수술재료로부터 병리조직학적 검사를 하여 생체내의 병변을 추구하는 분야를 외과병리학이라고 한다. 생검에는 쐐기생검, 천자침생검, 꿰뚫기식생검, 내시경생검 외에 세포진이라고 불리우는 박리세포진이나 세척세포진 등 떨어진 세포를 도말검사하는 방법이 포함된다. |
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| 영문 | target tissue | 한글 | 표적조직 |
|---|---|---|---|
| 설명 | 호르몬에 대하여 표적이 되는 세포라는 의미로서 그 호르몬에 대한 수용체를 가지고 있는 세포. 예를 들어 인슐린은 인슐린 수용체를 가진 세포를 표적세포로 하여 이 세포에만 작용한다. |
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| 영문 | subcutaneous tissue, subcutis | 한글 | 피하조직 |
|---|---|---|---|
| 설명 | 피부에서 진피의 아랫부분을 말함. 여기에는 지방조직이 많다. 기능은 열의 격리, 충격흡수, 영양저장소 등이다. |
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| PLAT | plasminogen activator, tissue-type |
|---|---|
| rh-tPA | recombinant tissue plasminogen activator |
| rTPA/rtPA | recombinant tissue plasminogen activator |
| rt-PA | recombinant tissue plasminogen activator |
| TPA | tannic acid, polyphosphomolybdic acid, and amino acid; 12-0-tetradecanoyl-phorbol-13-acetate; third-... |
| virus activation | The mechanism by which latent viruses, such as genetically transmitted tumour viruses or prophages of lysogenic bacteria, are induced to replicate and are released as infectious viruses. It may be effected by various endogenous and exogenous stimuli, including B-cell lipopolysaccharides, glucocorticoid hormones, halogenated pyrimidines, ionizing radiation, ultraviolet light, and superinfecting viruses. (12 Dec 1998) |
|---|---|
| cis activation | <molecular biology> Activation of a gene by an activator located on the same chromosome i.e. Not by a diffusible product. (18 Nov 1997) |
| complement activation | The sequential activation of serum components c1 through c9, initiated by an erythrocyte-antibody complex or by microbial polysaccharides and properdin, and producing an inflammatory response. (12 Dec 1998) |
| platelet activation | A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable haemostatic plug. (12 Dec 1998) |
| neutron activation analysis | Activation analysis in which the specimen is bombarded with neutrons. Identification is made by measuring the resulting radioisotopes. (12 Dec 1998) |
| neutrophil activation | The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonised particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil. (12 Dec 1998) |
| EEG activation | The low voltage, fast pattern of attentive wakefulness. (05 Mar 2000) |
| trans-activation (genetics) | Increased rate of gene expression directed by either viral or cellular proteins. These regulatory factors (diffusible gene products) act in trans -- that is, act on homologous or heterologous molecules of DNA. (cis-acting factors act only on homologous molecules.) (12 Dec 1998) |
| energy of activation | Energy that must be added to that already possessed by a molecule or molecules in order to initiate a reaction; usually expressed in the Arrhenius equation relating a rate constant to absolute temperature. (05 Mar 2000) |
| enzyme activation | Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1) activation by ions (activators); 2) activation by cofactors (coenzymes); and 3) conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme. (12 Dec 1998) |
| juxtacrine activation | Activation of target cells by membrane anchored growth factors, also used for activation of leucocytes by PAF bound to endothelial cell surface. (18 Nov 1997) |
| feedback activation | The activation of an enzyme by an end product of a biochemical pathway in which that enzyme plays a part. For example, the activation of factors VIII and V by thrombin during blood clotting. (05 Mar 2000) |
| feed-forward activation | The activation of an enzyme by a precursor of the substrate of that enzyme. (05 Mar 2000) |
| upstream activation site | A DNA sequence that regulates transcription like an enhancer but does notwork if its located downstream from a promoter. (09 Oct 1997) |
| low-activation materials | <radiobiology> In fission reactors, one is forced to deal with the radioactive byproducts of the fission process, but in fusion reactors one generally has a choice of what materials to expose to neutrons produced by the fusion process. A major problem for fusion reactors is developing materials (such as for the reactor vacuum vessel structure) which can be exposed to high levels of neutron bombardment without becoming permanently radioactive. Candidate structural materials which have relatively low induced radiactivation (generally relative to stainless steel) are known as low-activation materials, these include titanium, vanadium, and silicon-carbide. (09 Oct 1997) |