| 영문 | complement fixation reaction | 한글 | 보체결합 반응, 도움체결합반응 |
|---|---|---|---|
| 설명 | 항체와의 반응에 있어서 보체와 결합하는 항체를 검사하는 방법으로, 이 반응은 최초에 기지항원, 피검혈청 및 보체를 혼합한다. 제2단계에서는 적혈구와 이것에 대응하는 용혈소의 혼합액을 가한다. 본 반응후 용혈이 일어나지 않으면 본체는 항원항체결합물에 결합한 것이 되어 양성이 되지만, 용혈이 일어난 경우 보체는 결합하지 않아 소비되지 않기 때문에 음성이 된다. 본 반응은 기지혈청을 써서 항원검출에 응용할 수 있으며, 마이코플라스마, 리케챠, 클라미디아, 바이러스, 매독 등의 진단에 쓰인다. |
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| 영문 | transfusion reaction | 한글 | 수혈부작용, 수혈반응 |
|---|---|---|---|
| 설명 | 수혈하였을 때에 환자에게 일어나는 반응. 알레르기 반응과 용혈 반응이 있다. |
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| 영문 | graft versus host reaction | 한글 | 이식편대 숙주반응 |
|---|---|---|---|
| 설명 | 면역이란 자신의 것과 자신의 것이 아닌 것을 구분해서 자신의 것이 아닌 것을 공격하여 생물학적 활성을 없애거나 제거하는 것이다. 이 면역은 주로 혈액에 있는 세포에 의해서 이루어진다. 특히 림프구는 이 면역에 중추적인 역할을 하는 세포이다. 이식편대숙주반응이라는 것은 이식되어온 조직에 존재하는 타인의 혈구들이 숙주의 세포를 공격하는 것을 말한다. 즉 이식되어온 조직과 함께 들어온 혈구들이 이식을 받은 사람의 세포를 타인의 것으로 인지해서 공격하는 현상이다. 이것은 이식을 받은 사람의 면역상태가 정상적일 경우에는 일어나지 않는데 왜냐하면 면역상태가 정상일 경우에는 이식되어온 장기와 더불어 들어온 타인의 혈구들을 이식을 받은 사람의 혈구가 타인의 것으로 인지해서 공격을 하고 숫적으로 유리하여 모두 죽일 수가 있기 때문이다. |
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| TR | recovery time; rectal temperature; repetition time; residual tuberculin; terminal repeat; tetrazoliu... |
|---|---|
| LR | labeled release; laboratory references; laboratory report; labor room; lactated Ringer [solution]; l... |
| ST | esotropia; scala tympani; scaphotrapezoid; sclerotherapy; sedimentation time; semitendinosus; sensor... |
| TT | tablet triturate; tactile tension; tendon transfer; test tube; testicular torsion; tetanus toxin; te... |
| PTR | patellar tendon reflex; patient termination record; patient to return; peripheral total resistance; ... |
| constant | A quantity that, under stated conditions, does not vary with changes in the environment. (05 Mar 2000) |
|---|---|
| constant coupling | Where several premature beats are seen, the interval between each of them and the preceding normal beat is constant. Synonym: constant coupling. Variable coupling, where several extrasystoles are seen, the interval between each of them and the preceding sinus beat varies. (05 Mar 2000) |
| constant field equation | An equation derived to predict membrane potentials in terms of the membrane's permeability to ions and their concentrations on either side. Synonym: constant field equation, Goldman-Hodgkin-Katz equation, GHK equation. (05 Mar 2000) |
| constant infusion pump | An electrically driven device for delivery from a reservoir of a constant, often very small, volume of solution over a prolonged period of time. (05 Mar 2000) |
| constant region | The stem and forking part of the Y-shaped antibody protein, consisting of amino acid chains, that is exactly the same in all antibody molecules within the same individual. (The ends of the Y-shaped molecule will vary widely between different antibodies). (09 Oct 1997) |
| haemoglobin Constant Spring | An abnormal haemoglobin having an extended polypeptide chain (31 additional amino acid residues) on the a chain (thus, the a chain is 172 amino acids long); approximately 20% of the individuals with Hb H disease also have this defect. (05 Mar 2000) |
| Hill constant | A measure of cooperativity in a binding process. A Hill coefficient of 1 indicates independent binding, a value of greater than 1 shows positive cooperativity binding of one ligand facilitates binding of subsequent ligands at other sites on the multimeric receptor complex. Worked out originally for the binding of oxygen to haemoglobin (Hill coefficient of 2.8). (18 Nov 1997) |
| sedimentation constant | The constant s in Svedberg's equation for estimating the molecular weight of a protein from the rate of movement in a centrifugal field:where M is the molecular weight, R the gas constant, T the absolute temperature, D the diffusion constant (in square centimeters per second), V the partial specific volume of the protein, ρ the density of the solvent. The constant s, with dimensions of time per unit of field force (s = drb/dt /ω2ro where rb is the position at time t, r0 is the position at time 0, and ω is the angular velocity) is usually between 1 × 10-13 and 200 × 10-13 second. The Svedberg unit (S) is arbitrarily set at 1 × 10-13 second and is very often used to describe the sedimentation rate of macromolecules; e.g., 4 S RNA. Synonym: sedimentation coefficient. (05 Mar 2000) |
| specificity constant | Ratio of the maximum velocity (Vmax) or kcat to the true Km value for a specific substrate in an enzyme-catalyzed reaction. (05 Mar 2000) |
| Newtonian constant of gravitation | A universal constant relating the gravitational force, f., attracting two masses, m1 and m2, toward each other when they are separated by a distance, r, in the equation: f = G(m1m2/r2); it has the value of 6.67259 × 10-8 dyne cm2 g-2 = 6.67259 × 10-11 m3 kg-1 s-2 in SI units. (05 Mar 2000) |
| decay constant | <physics, radiobiology> The fraction of the amount of a radionuclide that undergoes transition per unit time. Formally: Lamda=dP/dt Where dP is the probability of a given nucleus undergoing spontaneous nuclear transition in the time interval dt. (16 Dec 1997) |
| diffusion constant | For the translational diffusion of solutes, diffusion is described by Fick's First Law, that states that the amount of a substance crossing a given area is proportional to the spatial gradient of concentration and the diffusion constant (D), that is related to molecular size and shape. A useful derived relationship is that the mean square distance moved by molecules in time t is 6Dt. (18 Nov 1997) |
| disintegration constant | <physics, radiobiology> The fraction of the amount of a radionuclide that undergoes transition per unit time. Formally: Lamda=dP/dt Where dP is the probability of a given nucleus undergoing spontaneous nuclear transition in the time interval dt. (16 Dec 1997) |
| dissociation constant | <chemistry> In a chemical equilibrium of form A + B = AB, the equilibrium concentrations (strictly, activities) of the reactants are related such that A x B/AB = a constant, Kd, the dissociation constant, that in this simplest case has the dimensions of concentration. When A is H, this is the acid dissociation constant often designated Ka and expressed as pKa (log10Ka). (18 Nov 1997) |
| dissociation constant of a base | Expressed by the general equation [B+][OH-]/[BOH] = Kb, where BOH is the undissociated base. (05 Mar 2000) |