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antilymphocyte globulin <protein> Antibodies which attach to and destroy lymphocytes. This may be used clinically by injection into a vein, for example in aplastic anaemia.
(13 Nov 1997)
b1C globulin The third component (C3) of complement.
See: component of complement.
(05 Mar 2000)
b1E globulin The fourth component (C4) of complement.
See: component of complement.
(05 Mar 2000)
b1F globulin The fifth component (C5) of complement.
See: component of complement.
(05 Mar 2000)
rabies immune globulin Globulin fraction of pooled plasma of high anti-rabies virus titre from immunised persons.
Synonym: rabies immunoglobulin.
(05 Mar 2000)
gamma globulin <immunology> A non-specific immunoglobulin (antibody) administered for the purpose of passive immunity. A common example is hepatitis A prophylaxis.
(27 Sep 1997)
measles immune globulin A sterile solution of globulin's derived from the blood plasma of normal adult human donors; it is prepared from immune serum globulin that complies with the measles antibody reference standard; a passive immunizing agent.
Synonym: measles immunoglobulin.
(05 Mar 2000)
globulin <protein> A simple globular protein which cannot be dissolved in pure water but which can be dissolved if a salt is added to the water. It can also be precipitated out of solution and into a solid with a solution of ammonium sulphate at 50% saturation.
Examples of globulin proteins are immunoglobulin and cryoglobulin.
(14 Oct 1997)
rho(d) immune globulin Immunizing agent containing IgG anti-rho(d) used for preventing rh immunization in rh-negative individuals exposed to rh-positive red blood cells.
(12 Dec 1998)
chickenpox immune globulin Globulin fraction of serum from persons recently recovered from herpes zoster infection; used to prevent infection of high-risk children.
Synonym: chickenpox immunoglobulin.
(05 Mar 2000)
pertussis immune globulin A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically.
Synonym: pertussis immunoglobulin.
(05 Mar 2000)
cold insoluble globulin <haematology> Name, now obsolete, originally given to fibronectin prepared from cryoprecipitate.
(18 Nov 1997)
plasma accelerator globulin <chemical> Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor v accomplishes this by forming a complex with factor xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor v leads to owren's disease.
Chemical name: Blood-coagulation factor V
(12 Dec 1998)
poliomyelitis immune globulin A sterile solution of globulin's that contains those antibodies normally present in adult human blood; it is a passive immunologic agent that attenuates or prevents poliomyelitis, measles, and infectious hepatitis, and confers temporary but significant protection against paralytic polio.
Synonym: poliomyelitis immunoglobulin.
(05 Mar 2000)
human gamma globulin A preparation of the proteins of liquid human plasma, containing the antibodies of normal adults; it is obtained from pooled liquid human plasma from a number of donors and may be prepared by precipitation with organic solvents under controlled conditions of pH, ionic strength, and temperature.
Synonym: human normal immunoglobulin.
(05 Mar 2000)
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