| ATG | adenine-thymidine-guanine antihuman thymocyte globulin; antithrombocyte globulin; antithymocyte glob... |
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| ChTK | chicken thymidine kinase |
| HSVtk | herpes simplex virus thymidine kinase |
| 3HT | tritiated thymidine |
| TDP | thermal death point; thoracic duct pressure; thymidine diphosphate; total degradation products |
| guanosine 5'-monophosphate | A major component of ribonucleic acids. Synonym: guanine ribonucleotide, guanosine 5'-monophosphate. Guanylic acid reductase (GMP reductase), an enzyme that catalyses the reaction of GMP with NADPH producing IMP, NH3, and NADP+; a part of the purine salvage pathway. Guanylic acid synthetase (GMP synthetase), an enzyme catalyzing the reaction of l-glutamine, XMP, and ATP to produce GMP, l-glutamate, AMP, and pyrophosphate; a key step in purine biosynthesis. Acronym: GMP (05 Mar 2000) |
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| guanosine monophosphate | A ribonucleotide which consists of the nitrogenous base guanine linked to the sugar ribose and which has a phosphate group attached to the 5th carbon atom of the ribose. (09 Oct 1997) |
| cyclic guanosine monophosphate | A cyclic version of the nucleotide guanosine monophosphate. It plays a role in communicating vision from the eyes to the brain. (09 Oct 1997) |
| cyclic uridine 3',5'-monophosphate | A cyclic nucleotide involved in metabolic regulation; inhibits the growth of some tumours. (05 Mar 2000) |
| cytidine monophosphate | A cytosine ribonucleotide (where the nitrogenous base cytosine is linked to the sugar ribose and a phosphate group) that helps make glycoproteins (a protein linked to a sugar or polysaccharide). (09 Oct 1997) |
| cytidine monophosphate n-acetylneuraminic acid | <chemical> A nucleoside monophosphate sugar which donates n-acetylneuraminic acid to the terminal sugar of a ganglioside or glycoprotein. Chemical name: D-glycero-beta-D-galacto-2-Nonulopyranosonic acid, 5-(acetylamino)-3,5-dideoxy-, 2-(hydrogen 5'-cytidylate) (12 Dec 1998) |
| xanthosine 5'-monophosphate | The monophosphoric ester of xanthosine. An intermediate in GMP biosynthesis. Synonym: xanthidylic acid, xanthine nucleotide, xanthylic acid. (05 Mar 2000) |
| hexose monophosphate pathway | <biochemistry> A pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final one being an oxidative decarboxylation to form a pentose phosphate. Diverges from this when glucose-6-phosphate is oxidized to ribose 5 phosphate by the enzyme glucose-6 phosphate dehydrogenase. This step reduces NADP to NADPH, generating a source of reducing power in cells for use in reductive biosyntheses. In plants, part of the pathway functions in the formation of hexoses from carbon dioxide in photosynthesis. Also important as source of pentoses, for example for nucleic acid biosynthesis. This pathway is the main metabolic pathway in neutrophils, congenital deficiency in the pathway produces sensitivity to infection. Alternative metabolic route to Embden Meyerhof pathway for breakdown of glucose. (18 Nov 1997) |
| hexose monophosphate shunt | The main metabolic pathway in activated neutrophils, rendering them relatively insensitive to inhibitors of oxidative phosphorylation. Congenital deficiency of the first enzyme in the shunt, glucose 6 phosphate dehydrogenase, produces a sensitivity to infection similar to that seen in chronic granulomatous disease. (18 Nov 1997) |
| nucleoside-monophosphate | A nucleotide, e.g., AMP. (05 Mar 2000) |
| deoxycytidine monophosphate | <chemical> Deoxycytidine (dihydrogen phosphate). A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions. Chemical name: 5'-Cytidylic acid, 2'-deoxy- (12 Dec 1998) |
| dolichol monophosphate mannose | <chemical> A lipophilic glycosyl carrier of the monosaccharide mannose in the biosynthesis of oligosaccharide phospholipids and glycoproteins. Chemical name: beta-D-Mannopyranose, 1-ester with dolichol dihydrogen phosphate (12 Dec 1998) |
| inosine monophosphate | <chemical> Inosine 5'-monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Chemical name: 5'-Inosinic acid (12 Dec 1998) |
| orotidine 5'-monophosphate | Orotidine 5'-monophosphate;an intermediate in the biosynthesis of the pyrimidine nucleosides (cytidine and uridine) that are found in nucleic acids. Synonym: orotidine 5'-monophosphate. (05 Mar 2000) |
| terpenyl monophosphate hydrolase | <enzyme> Hydrolyzes bornyl phosphate to borneol Registry number: EC 3.1.3.- (26 Jun 1999) |