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thromboblast Synonym: megakaryocyte.
Origin: thrombo-+ G. Blastos, germ
(05 Mar 2000)
thromboclastic 1. Dissolving or splitting up a thrombus.
2. <pharmacology> A thrombolytic agent.
Origin: Gr. Lysis = dissolution
(18 Nov 1997)
thrombocyst Thrombocystis
A membranous sac enclosing a thrombus.
Origin: thrombo-+ G. Kystis, a bladder
(05 Mar 2000)
thrombocytasthenia A term for a group of haemorrhagic disorders in which the platelets may be only slightly reduced in number, or even within the normal range, but are morphologically abnormal, or are lacking in factors that are effective in the coagulation of blood.
Origin: thrombocyte + G. Astheneia, weakness
(05 Mar 2000)
thrombocyte <haematology> Archaic name for a blood platelet.
(18 Nov 1997)
thrombocythaemia <haematology> Over-production of platelets.
See: essential thrombocythaemia.
(15 Oct 1997)
thrombocythemia Synonym: thrombocytosis.
Origin: thrombocyte + G. Haima, blood
(05 Mar 2000)
thrombocythemia, haemorrhagic A clinical syndrome characterised by repeated spontaneous haemorrhages and a remarkable increase in the number of circulating platelets.
(12 Dec 1998)
thrombocytic series The cells of successive stages in thrombocytic (platelet) development in the bone marrow, e.g., thromboblasts, thrombocytes.
(05 Mar 2000)
thrombocytin 5-hydroxytryptamine
thrombocytopathy General term for any disorder of the coagulating mechanism that results from dysfunction of the blood platelets.
Origin: thrombocyte + G. Pathos, suffering
(05 Mar 2000)
thrombocytopenia <haematology> A decrease in the number of platelets in the blood, resulting in the potential for increased bleeding and decreased ability for clotting.
Origin: Gr. Penia = poverty
(18 Nov 1997)
thrombocytopenia purpura <haematology> In severe thrombocytopenia, bleeding into skin leads to small petechial haemorrhages.
Primary thrombocytopenia purpura is of unknown cause but results from an autoimmune mechanism that causes platelet destruction.
Secondary thrombocytopenic purpura may result from drug-induced type II hypersensitivity in which platelets coated with antibody to the drug (which is acting as a hapten) are destroyed in a complement mediated reaction. It can also follow a viral upper respiratory infection and may be seen in association with lupus.
(15 Oct 1997)
thrombocytopenia-absent radius syndrome <syndrome> Tar stands for thrombocytopenia (low blood platelets) and aplasia (absence) of the radius (the long bone on the thumb-side of the forearm), features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the tar child. Alternative names include thrombocytopenia-absent radius syndrome, radial aplasia-thrombocytopenia syndrome, and tetraphocomelia-thrombocytopenia syndrome.
(12 Dec 1998)
thrombocytopenic purpura See: idiopathic thrombocytopenic purpura.
(05 Mar 2000)
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