| systemic chondromalacia | A degenerative disease of cartilage producing a bizarre form of arthritis, with collapse of the ears, the cartilaginous portion of the nose, and the tracheobronchial tree; death may occur from chronic infection or suffocation because of loss of stability in the tracheobronchial tree of autosomal origin. Synonym: chronic atrophic polychondritis, generalised chondromalacia, Meyenburg's disease, Meyenburg-Altherr-Uehlinger syndrome, relapsing perichondritis, systemic chondromalacia, von Meyenburg's disease. (05 Mar 2000) |
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| systemic circulation | The circulation of blood through the arteries, capillaries, and veins of the general system, from the left ventricle to the right atrium. Synonym: greater circulation. (05 Mar 2000) |
| systemic febrile diseases | Generic term for diseases characterised by fever. (05 Mar 2000) |
| systemic heart | The left atrium and ventricle, receiving the aerated blood from the lungs and propelling it throughout the body. (05 Mar 2000) |
| systemic hyalinosis | A rare recessively inherited deforming disorder of head, neck, and generalised cutaneous nodules or tumours in children with normal mentality; the lesions consist of fibroblasts separated by an eosinophilic hyalin stroma composed mostly of glycosaminoglycans. Synonym: systemic hyalinosis. (05 Mar 2000) |
| systemic lupus erythematosus | <immunology, nephrology, rheumatology> A disease of humans, probably autoimmune with antinuclear and other antibodies in plasma. Immune complex deposition in the glomerular capillaries is a particular problem. Acronym: SLE (19 Jan 1998) |
| systemic mastocytosis | Infiltration of many organ systems by mast cells with varied clinical manifestations that can include fever, weight loss, flushing, bronchospasm, rhinorrhoea, palpitations, dyspnea, diarrhoea, gastrointestinal bleeding, and hypotension. Synonym: systemic mastocytosis. (05 Mar 2000) |
| systemic myelitis | Inflammation confined to special tracts of the spinal cord. (05 Mar 2000) |
| systemic-onset juvenile chronic arthritis | See: Systemic-onset juvenile rheumatoid arthritis (still's disease). (12 Dec 1998) |
| systemic-onset juvenile rheumatoid arthritis | <rheumatology> A form of joint disease, arthritis, that presents with systemic upset. Clinical signs: high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis itself may not be immediately apparent but once apparent, it may persist after the systemic symptoms have resolved. Synonym: Still's disease. (03 Jul 1999) |
| systemic poisoning | Any disease of toxic origin. Synonym: systemic poisoning. Origin: toxico-+ G. -osis, condition (05 Mar 2000) |
| systemic sclerosis | <rheumatology> A multisystem disorder of unknown aetiology. It is characterised by fibrosis (scarring) of the skin, blood vessels and internal organs. Involvement of the gastrointestinal tract, heart, kidneys and lungs is common. (09 Jan 1998) |
| systemic therapy | <pharmacology> Treatment that reaches and affects cells all over the body. (16 Dec 1997) |
| systemic vascular resistance | An index of arteriolar compliance or constriction throughout the body; equal to the blood pressure divided by the cardiac output. (05 Mar 2000) |
| systemic venous hypertension | Increased pressure in the veins ultimately leading to the right atrium nearly always due to disease of the right heart but occasionally due to blockade of one or both venae cavae. (05 Mar 2000) |