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systemic mastocytosis Infiltration of many organ systems by mast cells with varied clinical manifestations that can include fever, weight loss, flushing, bronchospasm, rhinorrhoea, palpitations, dyspnea, diarrhoea, gastrointestinal bleeding, and hypotension.
Synonym: systemic mastocytosis.
(05 Mar 2000)
systemic myelitis Inflammation confined to special tracts of the spinal cord.
(05 Mar 2000)
systemic-onset juvenile chronic arthritis See: Systemic-onset juvenile rheumatoid arthritis (still's disease).
(12 Dec 1998)
systemic-onset juvenile rheumatoid arthritis <rheumatology> A form of joint disease, arthritis, that presents with systemic upset.
Clinical signs: high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis).
The arthritis itself may not be immediately apparent but once apparent, it may persist after the systemic symptoms have resolved.
Synonym: Still's disease.
(03 Jul 1999)
systemic poisoning Any disease of toxic origin.
Synonym: systemic poisoning.
Origin: toxico-+ G. -osis, condition
(05 Mar 2000)
systemic sclerosis <rheumatology> A multisystem disorder of unknown aetiology. It is characterised by fibrosis (scarring) of the skin, blood vessels and internal organs. Involvement of the gastrointestinal tract, heart, kidneys and lungs is common.
(09 Jan 1998)
systemic therapy <pharmacology> Treatment that reaches and affects cells all over the body.
(16 Dec 1997)
systemic vascular resistance An index of arteriolar compliance or constriction throughout the body; equal to the blood pressure divided by the cardiac output.
(05 Mar 2000)
systemic venous hypertension Increased pressure in the veins ultimately leading to the right atrium nearly always due to disease of the right heart but occasionally due to blockade of one or both venae cavae.
(05 Mar 2000)
juvenile chronic arthritis, systemic-onset See: Juvenile rheumatoid arthritis, systemic-onset (still's disease).
(12 Dec 1998)
juvenile rheumatoid arthritis, systemic-onset Also known as systemic-onset juvenile chronic arthritis. Still's disease presents with systemic (bodywide) illness including high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis may not be immediately apparent but it does always surface and it may persists long after the systemic symptoms are gone.
(12 Dec 1998)
panniculitis, lupus erythematosus A type of lupus erythematosus characterised by deep dermal or subcutaneous nodules, most often on the head, face, or upper arms. It is generally chronic and occurs most often in women between the ages of 20 and 45.
(12 Dec 1998)
chilblain lupus Skin lesions seen in patients with lupus erythematosus, resembling the small, hardened nodular areas of a cold injury called chilblains.
Synonym: chilblain lupus.
(05 Mar 2000)
chilblain lupus erythematosus Skin lesions seen in patients with lupus erythematosus, resembling the small, hardened nodular areas of a cold injury called chilblains.
Synonym: chilblain lupus.
(05 Mar 2000)
chronic discoid lupus erythematosus A form of lupus erythematosus in which cutaneous lesions are present; these commonly appear on the face and are atrophic plaques with erythema, hyperkeratosis, follicular plugging, and telangiectasia; in some instances systemic lupus erythematosis may develop.
Synonym: chronic discoid lupus erythematosus.
(05 Mar 2000)
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