| neoplastic syndromes, hereditary | The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumour tends to occur at an earlier than average age, individuals may have more than one primary tumour, the tumours may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance. (12 Dec 1998) |
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| nerve compression syndromes | Repeated or prolonged pressure on a nerve root or peripheral nerve leading to ischemia, the response to which is oedema above and below the source of pressure. If the pressure is not relieved, fibrosis tends to develop. Types of nerve compression syndromes are the neuropathy caused by intervertebral disk herniation, compression of the median nerve in the carpal tunnel, compression of the ulnar nerve in the elbow, and compression of the lateral cutaneous nerve of the thigh in meralgia paresthetica. This is also called pressure neuropathy. (12 Dec 1998) |
| dry eye syndromes | Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. (12 Dec 1998) |
| immunologic deficiency syndromes | Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral. (12 Dec 1998) |
| overgrowth syndromes | Conditions with multiple abnormalities including excessive growth. Early overgrowth syndromes that affecting children include the fragile x and beckwith-wiedemannn syndromes. Overactivity of the pituitary gland with overproductiuon of growth hormone causes overgrowth before adolescence and a distinctive pattern of overgrowth called acromegaly. (12 Dec 1998) |
| euthyroid sick syndromes | Abnormalities in thyroid hormone and thyroid-stimulating hormone levels, often simulating hypothyroidism, in euthyroid patients suffering some other illness, such as diabetes mellitus or liver cirrhosis. (12 Dec 1998) |