| keratoderma, palmoplantar | Group of mostly hereditary disorders characterised by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis). (12 Dec 1998) |
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| keratoderma, palmoplantar, diffuse | An autosomal dominant disorder characterised by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. There is more than one genotypically distinct form, each of which is clinically similar but histologically distinguishable. Diffuse palmoplantar keratoderma is distinct from palmoplantar keratoderma (keratoderma, palmoplantar), as the former exhibits autosomal dominant inheritance and hyperhidrosis is frequently present. (12 Dec 1998) |
| keratoderma plantare sulcatum | Hyperkeratosis and fissure formation on the soles. Synonym: cracked heel. (05 Mar 2000) |
| keratoderma symmetrica | The occurrence of symmetrical diffuse or patchy areas of hypertrophy of the horny layer of the epidermis on the palms and soles; a group of ectodermal dysplasias of considerable variety, and either autosomal dominant or recessive inheritance. Synonym: ichthyosis palmaris et plantaris, keratoderma palmaris et plantaris, keratoderma symmetrica, keratoma plantare sulcatum, keratosis palmaris et plantaris, tylosis palmaris et plantaris. (05 Mar 2000) |
| lymphedematous keratoderma | A profuse velvety papillomatous growth that develops large warty projections; caused by chronic lymphedema and stasis with maceration and associated infection. Synonym: lymphedematous keratoderma, lymphostatic verrucosis. (05 Mar 2000) |