| suppurative synovitis | Acute inflammation of synovial membranes, with purulent effusion into a joint, due to bacterial infection; the usual route of infection is hemic to the synovial tissue, causing destruction of the articular cartilage, and may become chronic, with sinus formation, osteomyelitis, deformity, and disability. Synonym: purulent synovitis, pyarthrosis, pyogenic arthritis, suppurative synovitis. (05 Mar 2000) |
|---|---|
| otitis media, suppurative | Inflammation of the middle ear with purulent discharge. (12 Dec 1998) |
| thyroiditis, suppurative | Inflammatory disease of the thyroid gland caused by bacteria, fungi, protozoa, or flatworms. (12 Dec 1998) |
| uveitis, suppurative | Intraocular infection caused mainly by pus-producing bacteria and rarely by fungi. The infection may be caused by an injury or surgical wound (exogenous) or by endogenous septic emboli in such diseases as bacterial endocarditis or meningococcaemia. (12 Dec 1998) |
| acute tubular necrosis | <nephrology> A kidney disorder that results in damage to the renal tubule cells leading to acute renal failure. Acute tubular necrosis can result from any condition which deprives the kidney of oxygen (ischaemia). Acute tubular necrosis may occur as a complication of shock, trauma or sepsis. Conditions such as diabetes or liver disease can predispose people to the development of acute tubular necrosis. Certain medications (for example aminoglycosides, amphotericin B, cyclosporine) are known to cause acute tubular necrosis as a toxic side effect. Radiopaque contrast dyes, used in some radiologic procedures, may also result in acute tubular necrosis as a rare complication from contrast dye use. Acronym: ATN (13 Nov 1997) |
| aseptic necrosis | <orthopaedics, pathology> Condition in which poor blood supply to an area of bone leads to bone death. Also called avascular necrosis and osteonecrosis. (12 Dec 1998) |
| avascular necrosis | <radiology> Aetiology (PLASTIC RAGS): P pancreatitis, L lupus, A alcohol, S steroids, T trauma, I idiopathic, infection, C caisson disease, collagen vascular disease, R radiation, rheumatoid arthritis, A amyloid, G Gaucher disease, S sickle cell disease findings: sclerosis, crescent sign, collapse (e.g., of femoral head) see also: staging (12 Dec 1998) |
| avascular necrosis staging | <radiology> Stage CT/X-ray bone scan I - cold/hot spot II sclerotic focus with osteopenic ring III crescent sign (subchondral lucency) IV articular collapse flattening of femoral head sensitivity 86% 78% specificity 79% 75% see also: avascular necrosis (AVN) (12 Dec 1998) |
| bridging hepatic necrosis | Area of liver necrosis which bridges adjacent portal areas and central veins; subsequent post-necrotic collapse and fibrosis is likely to result in cirrhosis. (05 Mar 2000) |
| p60 tumour necrosis factor receptor-associated kinase | <enzyme> Interacts with and causes phosphorylation of the cytoplasmic domain of the tnf receptor Registry number: EC 2.7.10.- Synonym: p60 tnf receptor-associated kinase, p60-trak (26 Jun 1999) |
| papillary necrosis | <radiology> Mnemonic: POST CARD, P pyelonephritis, O obstruction, S sickle cell disease, T TB, C cirrhosis (EtOH), A analgesics (phenacetin and aspirin), R renal vein thrombosis, D diabetes (12 Dec 1998) |
| receptors, tumour necrosis factor | Cell surface receptors that bind tumour necrosis factor and trigger changes which influence the behaviour of cells. The two recognised tumour necrosis factor receptors are designated alpha and beta receptors. Both receptors bind both alpha and beta tumour necrosis factors with high affinity, and both are members of the nerve growth factor receptor family. (12 Dec 1998) |
| caseous necrosis | Caseation necrosis, necrosis characteristic of certain inflammations (e.g., tuberculosis, histoplasmosis), which represents necrosis with loss of separate structures of the various cellular and histologic elements; affected tissue manifests the friable, crumbly consistency and dull, opaque quality observed in cheese. Synonym: caseous degeneration. (05 Mar 2000) |
| globus pallidus necrosis | <radiology> Carbon monoxide poisoning, barbiturate intoxication, cyanide poisoning, hydrogen sulfide poisoning, hypoglycaemia, hypoxia, hypotension, Leigh disease, Wilson disease CT: bilateral, symmetric low density in globus pallidus Cf: methanol intoxication leading to putamenal haemorrhagic necrosis (changes seen more laterally) (12 Dec 1998) |
| renal papillary necrosis | <nephrology> Necrosis of renal papillae, occurring in acute pyelonephritis, especially in diabetics, or in analgesic nephropathy; renal failure may result. Synonym: necrotizing papillitis. (05 Mar 2000) |