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molecule <chemistry> The result of two or more atoms combining by chemical bonding.
(09 Oct 1997)
hybrid molecule <molecular biology> A double-stranded nucleic acid molecule which was artificially created from two different single-stranded nucleic acid molecules from different sources, for the purpose of comparing their nucleotide sequences.
(09 Oct 1997)
hydrophilic signaling molecule <molecular biology> A type of molecule which, because it is easily dissolved in water (it is hydrophilic), can easily move through cell membranes and thus can be secreted from one cell and move into a target cell where it triggers a particular event. Many hormones and growth factors are hydrophilic signaling molecules.
(09 Oct 1997)
neural cell adhesion molecule See: NCAM.
(18 Nov 1997)
intercellular adhesion molecule See: ICAM.
(18 Nov 1997)
intercellular adhesion molecule-1 <chemical> A cell-surface ligand with a role in leukocyte adhesion and inflammation. Its production is induced by gamma-interferon and it is required for neutrophil migration into inflamed tissue.
Chemical name: Glycoprotein ICAM 1 (human clone pHRVr1 deblocked protein moiety reduced)
(12 Dec 1998)
organic molecule <chemistry> A molecule with a basic skeleton made up of a skeleton of carbon atoms plus hydrogen and oxygen atoms and, in proteins, nitrogen.
Organic molecules may also include isolated atoms of other elements.
(11 Jan 1998)
endothelial-leukocyte adhesion molecule 115,000 Mw molecule on the surface of endothelial cells that is involved in blood leukocyte attachment to vessel walls as well as emigration from the vessels into the tissues.
(05 Mar 2000)
A chain A polypeptide component of insulin containing 21 amino acyl residues, beginning with a glycyl residue (NH2-terminus); insulin is formed by the linkage of an A chain to a B chain by two disulfide bonds; the amino-acid composition of the A chain is a function of species.
Synonym: glycyl chain.
In general, one of the polypeptides in a multiprotein complex.
(05 Mar 2000)
alpha chain disease A vague or indefinite term; could be used for alpha-heavy-chain disease (a lymphoplasma cell proliferative disease usually seen in Mediterranean men, characterised by intestinal involvement with steatorrhoea, often progressive with fatal outcome) or a thalassaemia (a genetic abnormality in the alpha globin chain of haemoglobin).
(05 Mar 2000)
amino acids, branched-chain Amino acids which have a branched carbon chain.
(12 Dec 1998)
B chain A polypeptide component of insulin containing 30 amino acyl residues, beginning with a phenylalanyl residue (NH2-terminus); insulin is formed by the linkage of a B chain to an A chain by two disulfide bonds; the amino-acid composition of the B chain is a function of species.
Synonym: phenylalanyl chain.
(05 Mar 2000)
behaviour chain Related behaviours in a series in which each response serves as a stimulus for the next response.
(05 Mar 2000)
branched chain acyl-CoA oxidase <enzyme> Enzyme from human liver peroxisomes acts on both 2-methyl branched fatty acyl- and bile acid-CoA intermediates, unlike rat liver peroxisomes which have separate enzymes for branched chain fatty acids (pristanoyl-CoA) and bile acid-CoA; involved in beta-oxidation of fatty acids and bil
Registry number: EC 1.3.3.-
Synonym: 2-methyl-branched chain acyl-CoA oxidase, hbrcacox
(26 Jun 1999)
branched-chain fatty-acid-kinase <enzyme> From anaerobic spirochete ma-2
Registry number: EC 2.7.2.14
Synonym: isovalerate kinase, 2-methylbutyrate kinase, isobutyrate kinase
(26 Jun 1999)
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