| geranyl pyrophosphate-sabinene hydrate cyclase | <enzyme> Enzyme from sweet marjoram; catalyses cation-dependent cyclization of geranyl pyrophosphate to cis and trans sabinene hydrate, deriving oh from water, not from the pyrophosphate ester Registry number: EC 5.5.- Synonym: sabinene hydrate cyclase, sabinene hydrate synthase (26 Jun 1999) |
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| versiconal cyclase | <enzyme> From aspergillus parasiticus; catalyses the dehydration of versiconal to versicolorin b or c Registry number: EC 4.2.1.- (26 Jun 1999) |
| caryophyllene cyclase | <enzyme> Catalyses the cyclization of farnesyl pyrophosphate, probably by intramolecular electrophilic attack by c-1 bearing the pyrophosphate ester on c-11 of the terminal double bond to give a humulyl cation, which undergoes closure to a cyclobutyl intermediate and deprotonation at c-3 methyl to form (-) caryophyllene; mw 57 kD Registry number: EC 5.- (26 Jun 1999) |
| glutamine amidotransferase cyclase | <chemical> Possesses glutamine amidotransferase and cyclase activities; his7 isolated from saccharomyces cerevisiae catalyses the fifth and sixth steps of histidine biosynthesis. Synonym: his7 gene product (26 Jun 1999) |
| chanoclavin-I-cyclase | <enzyme> Converts chanoclavin I to agraclavin Registry number: EC 3.5.- (26 Jun 1999) |
| RNA 3'-terminal phosphate cyclase | <enzyme> ATP dependent; forms 2',3' terminal cyclic phosphate on RNA which is then the substrate for RNA ligase of hela cells Registry number: EC 6.5.- Synonym: RNA tph cyclase (26 Jun 1999) |
| guanylate cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| guanyl cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| guanylyl cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| cyclase | Descriptive name applied to an enzyme that forms a cyclic compound; e.g., adenylate cyclase. (05 Mar 2000) |
| purine imidazole-ring cyclase | <enzyme> Recyclises ring-opened purine formamidopyrimidines in irradiated DNA, restoring the c-8 to n-9 band, does not require ATP Registry number: EC 6.3.3.- Synonym: purir cyclase (26 Jun 1999) |
| humulene cyclase | <enzyme> Catalyses the cyclization of farnesyl pyrophosphate; probably by intramolecular electrophilic attack by c-1 bearing the pyrophosphate ester on c-11 of the terminal double bond to give a humulyl cation which is stabilised by deprotonation at c-9 to form all-trans humulene; mw 57 kD Registry number: EC 5.- (26 Jun 1999) |
| diguanylate cyclase | <enzyme> Converts 2GTP to bis-(3'-5')cyclic guanylic acid, via linear diguanosine tetraphosphate pppg 3'p5'g, releasing 1 pyrophosphate at each step Registry number: EC 4.6.1.- (26 Jun 1999) |
| tetracenomycin F2 cyclase | <enzyme> Catalyses the cyclization of the anthrone tcmf2 to the naphthacenone tcmf1 in the biosynthesis of antibiotic tcm c in streptomyces glaucescens by an intramolecular aldol condensation-dehydration Registry number: EC 4.1.2.- Synonym: tcmi protein (26 Jun 1999) |
| thienamycin cyclase | <enzyme> Isolated from streptomyces lividans Registry number: EC 5.- (26 Jun 1999) |