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incontinence of urine Inability to hold urine in the bladder. This is due to failure of voluntary control over the urinary sphincters resulting in involuntary passage of urine (wetting).
(12 Dec 1998)
oasthouse urine disease An inherited metabolic defect in the absorption of methionine which is converted by intestinal bacteria to alpha-hydroxybutyric acid; characterised by diarrhoea, tachypnea, and marked urinary excretion of alpha-hydroxybutyric acid (causing an odour like that of an oasthouse).
Origin: oast, kiln for drying hops, malt, or tobacco
(05 Mar 2000)
febrile urine Dark coloured, concentrated urine of strong odour, passed by one suffering from fever.
Synonym: feverish urine.
(05 Mar 2000)
feverish urine Dark coloured, concentrated urine of strong odour, passed by one suffering from fever.
Synonym: feverish urine.
(05 Mar 2000)
urine <physiology> In mammals, a fluid excretion from the kidneys; in birds and reptiles, a solid or semisolid excretion.
In man, the urine is a clear, transparent fluid of an amber colour and peculiar odour, with an average density of 1.02. The average amount excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous solution of urea, salt (sodium chloride), and uric acid, together with some hippuric acid and peculiar pigments. It usually has an acid reaction, owing to the presence of acid phosphates of soda or free uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter, and the daily average excretion is 35 grams (540 grains) of urea.75 gram (11 grains) of uric acid, and 16.5 grams (260 grains) of salt. Abnormally, it may contain sugar as in diabetes, albumen as in Bright's disease, bile pigments as in jaundice, or abnormal quantities of some one or more of the normal constituents.
Origin: F. Urine, L. Urina; akin to urinari to plunge under water, to dive, Gr. Urine; cf. Skr. Var water, Icel. R drizzling rain, AS. Waer the sea.
Source: Websters Dictionary
(01 Mar 1998)
urine catecholamine A test that measures the level of catecholamines or their metabolites in the urine. A 24 hour urine sample is necessary for this assay. Elevations may be seen in pheochromocytoma or neuroblastoma. Normal urine levels of adrenaline should be: 0.5 to 20 mcg/ml and normal urine levels of noradrenaline should be 15 to 80 mcg/ml.
(27 Sep 1997)
urine immunofixation A special laboratory technique that is used to identify specific proteins in the blood or urine. It has greatest application in the identification (and monitoring) of monoclonal proteins that are produced in conditions like Waldenstom's macroglobulinaemia and multiple myeloma.
(27 Sep 1997)
urine metanephrine A test that measures the level of catecholamines or their metabolites in the urine. A 24 hour urine sample is necessary for this assay. Elevations may be seen in pheochromocytoma or neuroblastoma. Normal urine levels of adrenaline should be: 0.5 to 20 mcg/ml and normal urine levels of noradrenaline should be 15 to 80 mcg/ml.
(27 Sep 1997)
acetoacetyl-acyl carrier protein synthase <enzyme> E coli enzyme, that catalyses condensation of malonyl-acyl carrier protein plus acetyl-acyl carrier protein; not inhibited by cerulenin
Registry number: EC 2.3.1.-
Synonym: acetoacetyl-acp synthase
(26 Jun 1999)
acid soluble spore protein <molecular biology> A DNA binding protein in the spores of some bacteria, thought to stabilise the DNA in an A configuration, so protecting it from cleavage by enzymes or UV light.
(18 Nov 1997)
acute-phase protein <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor).
Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold.
Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability.
These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers.
See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity.
(25 Jun 1999)
acyl-(acyl-carrier-protein)-phospholipid acyltransferase <enzyme> Catalyses the formation of phosphatidylethanolamine from acyl-acyl carrier protein and 2-acyl-sn-glycero-3-phosphoethanolamine
Registry number: EC 2.3.1.40
Synonym: 2-acyl-gpe acyltransferase, 2-acylglycerophosphoethanolamine acyltransferase
(26 Jun 1999)
acyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferase <enzyme> E coli enzyme involved in lipid a biosynthesis; uses beta-hydroxymyristoyl-acyl carrier protein to form udp-3-monoacyl-n-acetylglucosamine; amino acid sequence given in second source
Registry number: EC 2.3.1.129
Synonym: udp-aguatransferase, lpxa protein, udp-n-acetylglucosamine-3-acyltransferase, udp-n-acetylglucosamine 3-o-acyltransferase, udp-3-o-(r-3-hydroxymyristoyl)glucosamine-n-acyltransferase, lpxd protein, fira gene product, fira protein
(26 Jun 1999)
acyl carrier protein <protein> A small (77 peptides long) protein which binds six other enzymes involved in fatty acid synthesis. It was first isolated in E. Coli bacteria.
(09 Oct 1997)
acyl carrier protein acylase <enzyme> From E coli
Registry number: EC 2.3.1.-
Synonym: acp acylase
(26 Jun 1999)
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