| Merrifield synthesis | The synthesis of peptides and proteins via an automated system on carrier polymers. (05 Mar 2000) |
|---|---|
| chiral synthesis | <chemistry> The production of chiral compounds in only one enantiomer, or handedness. (See chirality) (05 Jan 1998) |
| coordinated enzyme synthesis | The regulatory mechanism where an entire group of different enzymes, all of which play a part in the same metabolic process, is synthesised at the same time. This comes about because the chemical signal to begin synthesis of each enzyme is the same for all of them. (09 Oct 1997) |
| protein synthesis | The process in which individual amino acids, whether of exogenous or endogenous origin, are connected to each other in peptide linkage in a specific order dictated by the sequence of nucleotides in DNA; this governing sequence is conveyed to the synthesizing apparatus in the ribosomes by mRNA, formed by base-pairing on the DNA template. (05 Mar 2000) |
| protein synthesis inhibitor | Compounds which inhibit the synthesis of proteins. They are usually antibiotics or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the the a site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (12 Dec 1998) |
| nucleic acid synthesis inhibitors | Compounds that inhibit cell production of DNA or RNA. (12 Dec 1998) |
| synthesis | 1. <biochemistry, chemistry> The artificial building up of a chemical compound, by the union of its elements or from other suitable starting materials. 2. <psychiatry> The integration of the various elements of the personality, the opposite of analysis. Origin: Gr. = a putting together, composition (19 Jan 1998) |
| synthesis of continuity | Healing of the edges of a wound or fracture. (05 Mar 2000) |
| synthesis period | The period of the cell cycle when there is synthesis of DNA and histone; it occurs between Gap1 and Gap2. Synonym: S phase. (05 Mar 2000) |
| DNA synthesis | <molecular biology> The linking together of nucleotides (as deoxyribonucleotide triphosphates) to form DNA. In vivo, most synthesis is DNA replication, but incorporation of precursors also occurs in repair. In the special case of retroviruses, DNA synthesis is directed by an RNA template (see reverse transcriptase). (18 Nov 1997) |
| enzymatic synthesis | Synthesis by enzymes. See: biosynthesis. (05 Mar 2000) |
| Kiliani-Fischer synthesis | A synthetic procedure for the extension of the carbon atom chain of aldoses by treatment with cyanide; hydrolysis of the cyanohydrins followed by reduction of the lactone yields the homologous aldose; with this method, d-glucose and d-mannose can be synthesised from d-arabinose. (05 Mar 2000) |
| unscheduled DNA synthesis | <cell biology, molecular biology> Any synthesis of DNA that happens ouside the S phase of the cell cycle. (13 Nov 1997) |
| accelerated phase of leukaemia | Refers to chronic myelogenous leukaemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase, but not as high as in the blast phase. (12 Dec 1998) |
| acceleration phase | <cell biology, cell culture> A period of increasing growth before the log phase in a culture of microbes. After the culture is started on a medium, at first there is no growth (the lag phase) and then the microbes start to gradually grow (acceleration phase) until they reach a constant maximum rate of growth (log phase). (15 Jan 1998) |