| MIS | management information system; medical information service; meiosis-inducing substance; minimally in... |
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| ASA | acetylsalicylic acid; active systemic anaphylaxis; Adams-Stokes attack; American Society of Anesthes... |
| BK-A | basophil kallikrein of anaphylaxis |
| ECFA, ECF-A | eosinophilic chemotactic factor of anaphylaxis |
| PAF-A | platelet-activating factor of anaphylaxis |
| slow ray | <microscopy> The slower of the two rays created by a crystal or fibre and the one that travels the path of higher refractive index. (05 Aug 1998) |
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| slow scan | <microscopy> A system of video scanning in which the time used to read each line has been increased in comparison to standard video. The bandwidth needed to faithfully transmit or record the signal is reduced in inverse ratio to the scanning time. Slow scan allows the video signal to be transmitted over a telephone line, or line scans to be registered on a chart recorder. (19 Jan 1998) |
| slow virus | 1. <virology> Specifically one of the Lentivirinae 2. Any virus causing a disease that has a very slow onset. Diseases such as sub acute spongiform encephalopathy, Aleutian disease of mink, scrapie, kuru and Creutzfeldt Jacob disease may be caused by slow viruses. See: prion. (18 Nov 1997) |
| slow virus disease | A disease that follows a slow, progressive course spanning months to years, frequently involving the central nervous system, and ultimately leading to death, such as visna and maedi of sheep, caused by viruses of the subfamily Lentivirinae (family Retroviridae), and subacute sclerosing panencephalitis, seemingly caused by the measles virus; spongiform encephalopathies including kuru of man, scrapie of sheep, and transmissible encephalopathy of mink may also be classified under slow virus disease but their respective aetiologic agents have not been adequately characterised. (05 Mar 2000) |
| slow virus diseases | Diseases of viral origin, characterised by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as subacute sclerosing panencephalitis, progressive multifocal leukoencephalopathy (leukoencephalopathy, progressive multifocal), and aids. Diseases produced by unconventional agents were originally considered part of this group. They are now called prion diseases. (12 Dec 1998) |
| active anaphylaxis | Reaction following inoculation of antigen in a subject previously sensitised to the specific antigen, in contrast to passive anaphylaxis. (05 Mar 2000) |
| aggregate anaphylaxis | <pharmacology> As opposed to prophylaxis. A system or treatment that leads to damaging effects on the organism. <immunology> Now reserved for those inflammatory reactions resulting from combination of a soluble antigen with IgE bound to a mast cell that leads to degranulation of the mast cell and release of histamine and histamine like substances, causing localised or global immune reponses. Results in an acute allergic reaction with shortness of breath, rash, wheezing, hypotension. See: hypersensitivity. (18 Nov 1997) |
| anaphylaxis | <pharmacology> As opposed to prophylaxis. A system or treatment that leads to damaging effects on the organism. <immunology> Now reserved for those inflammatory reactions resulting from combination of a soluble antigen with IgE bound to a mast cell that leads to degranulation of the mast cell and release of histamine and histamine like substances, causing localised or global immune reponses. Results in an acute allergic reaction with shortness of breath, rash, wheezing, hypotension. See: hypersensitivity. (18 Nov 1997) |
| antiserum anaphylaxis | A reaction resulting from inoculation of antigen in an animal previously inoculated intravenously with specific antiserum from another animal, a latent period being required between the two inoculations. Synonym: antiserum anaphylaxis. (05 Mar 2000) |
| generalised anaphylaxis | The immediate response, involving smooth muscles and capillaries throughout the body of a sensitised individual, that follows intravenous (and occasionally intracutaneous) injection of antigen (allergen). See: anaphylactic shock. Synonym: systemic anaphylaxis. (05 Mar 2000) |
| passive anaphylaxis | A reaction resulting from inoculation of antigen in an animal previously inoculated intravenously with specific antiserum from another animal, a latent period being required between the two inoculations. Synonym: antiserum anaphylaxis. (05 Mar 2000) |
| passive cutaneous anaphylaxis | An evanescent cutaneous reaction occurring when antibody is injected into a local area on the skin and antigen is subsequently injected intravenously along with a dye. The dye makes the rapidly occurring capillary dilatation and increased vascular permeability readily visible by leakage into the reaction site. Pca is a sensitive reaction for detecting very small quantities of antibodies and is also a method for studying the mechanisms of immediate hypersensitivity. (12 Dec 1998) |
| passive cutaneous anaphylaxis test | An animal is injected intradermally with antibody (usually IgE) and subsequently challenged intravenously with a mixture of antigen and Evans blue dye 24-48 hours later. A dark blue area indicates a positive reaction due to the leakage of the dye at the site of antigen-antibody reactions. (05 Mar 2000) |
| reversed anaphylaxis | An anaphylactic reaction induced in an animal injected with a specific antigen, which will bind to reactive tissue, and then, after a latent period, with serum from another animal previously sensitised to the identical antigen. Synonym: reversed anaphylaxis. (05 Mar 2000) |
| reversed passive anaphylaxis | An anaphylactic reaction induced in an animal injected with a specific antigen, which will bind to reactive tissue, and then, after a latent period, with serum from another animal previously sensitised to the identical antigen. Synonym: reversed anaphylaxis. (05 Mar 2000) |