| PL7a receptor-tyrosine kinase | <enzyme> A member of the eph receptor tyrosine kinase subfamily; shows 80% identity with myk-1; genbank l43622 Registry number: EC 2.7.1.- Synonym: pl7a protein (26 Jun 1999) |
|---|---|
| Csk-like protein-tyrosine kinase | <enzyme> Phosphorylates c-terminal conserved tyr of src family members; from mouse brain; has 52% identity with mouse csk; mw 52 kD; genbank u05210 Registry number: EC 2.7.1.- Synonym: ctk (kinase), ctk gene product, csk-type protein-tyrosine kinase, ntk (kinase), bhk (kinase) (26 Jun 1999) |
| protein-tyrosine kinase | <enzyme> An enzyme that catalyses the phosphorylation of tyrosine residues in proteins with ATP or other nucleotides as phosphate donors.12. Chemical name: ATP:protein-tyrosine O-phosphotransferase Registry number: EC 2.7.1.112 (12 Dec 1998) |
| nonreceptor protein tyrosine kinase | <enzyme> Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single transmembrane domain and an intracellular tyrosine kinase domain and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (18 Nov 1997) |
| insulin receptor protein-tyrosine kinase | <enzyme> A catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of the insulin receptor. Registry number: EC 2.7.1.- (12 Dec 1998) |
| TCK receptor-tyrosine kinase | <enzyme> A member of the eph receptor tyrosine kinase subfamily; expressed during xenopus development; shows 79% amino acid identity to hek2; genbank l43621 Registry number: EC 2.7.1.- Synonym: tck protein (26 Jun 1999) |
| Tec protein-tyrosine kinase | <enzyme> Member of the cytoplasmic ptks of the non-src family; associates with lyn ptk; n-terminal amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: tec ptk, tec kinase, tec tyrosine kinase (26 Jun 1999) |
| TIE-2 receptor tyrosine kinase | <enzyme> Expressed in developing vascular endothelial cells; unlike tie-1, also expressed in lens epithelium and heart epicardium; has the same organization of amino acid sequence motifs characteristic of tie-1; aa sequence of the intracellular and extracellular regions of tie-1 and tie-2 are 79% and 32% identical, respectively; aa sequence of both kinases given in first source Registry number: EC 2.7.10.- Synonym: tie-2-rtk (26 Jun 1999) |
| tie receptor tyrosine kinase | <enzyme> From human leukaemia cells; expressed in developing vascular endothelial cell; has homology with egf, bfgf, csf-1, pdgf and stem cell factor receptors; ligand and biologic function not known as of 12/92; tie-1 receptor tyrosine kinase is rat homolog of tie receptor tyrosine kinase; aa sequence known Registry number: EC 2.7.10.- Synonym: tie-1 receptor tyrosine kinase, tie-1 rtk (26 Jun 1999) |
| emb protein-tyrosine kinase | <enzyme> Isolated from murine mast cells Registry number: EC 2.7.1- Synonym: emb ptk (26 Jun 1999) |
| emt protein-tyrosine kinase | <enzyme> Isolated from murine mast cells Registry number: EC 2.7.1.- Synonym: emt ptk, itk protein, itk gene product, tsk protein, inducible t cell kinase (26 Jun 1999) |
| epidermal growth factor receptor protein-tyrosine kinase | <enzyme> The catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of epidermal growth factor receptor. Registry number: EC 2.7.1.- (12 Dec 1998) |
| estradiol receptor tyrosine kinase | <enzyme> Calcium and calmodulin dependent Registry number: EC 2.7.1.- Synonym: ertk (26 Jun 1999) |
| tyrosine kinase | <enzyme> Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single transmembrane domain and an intracellular tyrosine kinase domain and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (18 Nov 1997) |
| lymphocyte specific protein tyrosine kinase p56(lck) | <enzyme> This enzyme is a lymphoid specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the il-2 receptor, and is thought to be involved in the earliest steps of tcr-mediated T-cell activation. Registry number: EC 2.7.11.- (12 Dec 1998) |