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env, environ environment, environmental
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H&E hematoxylin and eosin [stain]; hemorrhage and exudate; heredity and environment
HEV health and environment; hemagglutinating encephalomyelitis virus; hepatitis E virus; hepato-encephal...
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KAP Knowledge, Attitudes and Practices
VE Virtual Environment
ERK 1-extracellular signal-regulated kinase
STAT 2/signal transducer and activator of transcription
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complete transduction Transduction in which the transferred genetic fragment is fully integrated in the genome of the recipient bacterium.
(05 Mar 2000)
high frequency transduction Specialised transduction in which the donor bacterium contains not only the transducing, defective probacteriophage but also nondefective prophage that serves as "helper" virus, enabling most of the defective prophage particles to develop sufficiently to function as transducing agents.
(05 Mar 2000)
specialised transduction Transduction in which the bacteriophage strain is able to transfer only some, or only one, of the donor bacterium genes.
Synonym: specific transduction.
(05 Mar 2000)
specific transduction Transduction in which the bacteriophage strain is able to transfer only some, or only one, of the donor bacterium genes.
Synonym: specific transduction.
(05 Mar 2000)
transduction 1. <molecular biology> The transfer of a gene from one bacterium to another by a bacteriophage.
In generalised transduction any gene may be transferred as a result of accidental incorporation during phage packaging. In specialised transduction only specific genes can be transferred, as a result of improper recombination out of the host chromosome of the prophage of a lysogenic phage.
Transduction is an infrequent event but transducing phages have proved useful in the genetic analysis of bacteria.
2. <biology, physics> The conversion of a signal from one form to another.
For example: various types of sensory cells convert or transduce light, pressure, chemicals, etc. Into nerve impulses and the binding of many hormones to receptors at the cell surface is transduced into an increase in cAMP within the cell.
(17 Mar 1998)
transduction, genetic Transfer of bacterial DNA by phages from the infected bacterium in which the DNA originates to another bacterium.
(12 Dec 1998)
low frequency transduction Specialised transduction in which only a small portion of the prophage particles, because of their defectiveness, are able to develop sufficiently to serve as effective transducing agents.
(05 Mar 2000)
COOH-terminal signal transamidase <enzyme> Present in the endoplasmic reticulum; catalyses concomitant cleavage of the signal peptide of nascent proteins destined to be processed to a glycosylphosphatidylinositol (gpi) and addition of the gpi anchor
Registry number: EC 2.3.2.-
Synonym: cooh-ts-transamidase, gpi transamidase, gpti transamidase
(26 Jun 1999)
signal 1. Noticeable; distinguished from what is ordinary; eminent; remarkable; memorable; as, a signal exploit; a signal service; a signal act of benevolence. "As signal now in low, dejected state As erst in highest, behold him where he lies." (Milton)
2. Of or pertaining to signals, or the use of signals in conveying information; as, a signal flag or officer. The signal service, a bureau of the government (in the United States connected with the War Department) organised to collect from the whole country simultaneous raports of local meteorological conditions, upon comparison of which at the central office, predictions concerning the weather are telegraphed to various sections, where they are made known by signals publicly displayed. Signal station, the place where a signal is displayed; specifically, an observation office of the signal service.
Synonym: Eminent, remarkable, memorable, extraordinary, notable, conspicuous.
Origin: From signal, n., cf. F. Signale.
Source: Websters Dictionary
(01 Mar 1998)
signal detection (psychology) A theory of psychophysics which characterises not only the acuity of an individual's discrimination but also the psychological factors that bias his judgment.
(12 Dec 1998)
signal node A firm supraclavicular lymph node, especially on the left side, sufficiently enlarged that it is palpable from the cutaneous surface; such a lymph node is so termed because it may be the first recognised presumptive evidence of a malignant neoplasm in one of the viscera. A signal node that is known to contain a metastasis from a malignant neoplasm is sometimes designated by an old eponym, Troisier's ganglion.
Synonym: jugular gland, Virchow's node.
(05 Mar 2000)
signal peptidase A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum.
See: signal recognition particle.
(18 Nov 1997)
signal peptidase complex A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum.
See: signal recognition particle.
(18 Nov 1997)
signal peptide A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum.
See: signal recognition particle.
(18 Nov 1997)
signal peptide p25-subunit IV cytochrome oxidase <chemical> Similar in action to melittin
Synonym: p25 presequence peptide-cytochrome oxidase, pre-ctox p25
(26 Jun 1999)
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