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phosphogluconate pathway <biochemistry> This oxidative pathway starts with glucose-6-phosphate andeventually results in the creation of pentose phosphates and NADPH.
(09 Oct 1997)
complement pathway, alternative The complement activation sequence initiated by the activation of complement factor c3, which is triggered by the interaction of microbial polysaccharides and properdin without participation of an antigen-antibody reaction.
(12 Dec 1998)
complement pathway, classical The sequential activation of complement, initiated by antigen-antibody complex and the binding of complement factor c1q to the fc region of the antibody.
(12 Dec 1998)
polyol pathway A pathway responsible for d-fructose formation from sorbitol; increases in activity as the glucose concentration rises in diabetes.
Synonym: polyol pathway.
(05 Mar 2000)
critical pathway Schedules of medical and nursing procedures, including diagnostic tests, medications, and consultations designed to effect an efficient, coordinated program of treatment.
(12 Dec 1998)
Hatch Slack Kortshak pathway <biochemistry> Metabolic pathway responsible for primary carbon dioxide fixation in C4 plant photosynthesis.
The enzymes that are found in mesophyll chloroplasts include PEP carboxylase, that adds carbon dioxide to phosphoenolpyruvate to give the 4 carbon compound, oxaloacetate. Four carbon compounds are transferred to bundle sheath chloroplasts, where the carbon dioxide is liberated and re fixed by the Calvin Benson cycle.
The Hatch Slack Kortshak pathway permits efficient photosynthesis under conditions of high light intensity and low carbon dioxide concentration, avoiding the nonproductive effects of photorespiration.
Acronym: HSK pathway
(15 Nov 1997)
principal sensory nucleus of the trigeminus <anatomy, nerve> The term commonly used to designate the nucleus pontis nervi trigeminalis; located in pons lateral to the motor trigeminal nucleus; receives primary sensory (touch and pressure) input via the trigeminal nerve, projects to ventral posteromedial nucleus of thalamus.
Synonym: nucleus sensorius principalis nervi trigemini, nucleus sensorius superior nervi trigemini, principal sensory nucleus of the trigeminus.
(05 Mar 2000)
principal sensory nucleus of trigeminal nerve <anatomy, nerve> The term commonly used to designate the nucleus pontis nervi trigeminalis; located in pons lateral to the motor trigeminal nucleus; receives primary sensory (touch and pressure) input via the trigeminal nerve, projects to ventral posteromedial nucleus of thalamus.
Synonym: nucleus sensorius principalis nervi trigemini, nucleus sensorius superior nervi trigemini, principal sensory nucleus of the trigeminus.
(05 Mar 2000)
salvage pathway <biochemistry> A recycling metabolic pathway in which biomolecules such as nucleotides are synthesised from intermediates in the degradative pathway for those biomolecules. The intermediate materials would otherwise be waste products.
(14 Oct 1997)
hereditary sensory radicular neuropathy Neuropathy characterised by the occurrence of severe, relapsing foot ulcerations of neuropathic origin, destruction of terminal digits of feet and hands, and a loss of sensation; autosomal dominant inheritance is associated with onset in the second decade or later.
(05 Mar 2000)
hexose monophosphate pathway <biochemistry> A pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final one being an oxidative decarboxylation to form a pentose phosphate.
Diverges from this when glucose-6-phosphate is oxidized to ribose 5 phosphate by the enzyme glucose-6 phosphate dehydrogenase. This step reduces NADP to NADPH, generating a source of reducing power in cells for use in reductive biosyntheses.
In plants, part of the pathway functions in the formation of hexoses from carbon dioxide in photosynthesis. Also important as source of pentoses, for example for nucleic acid biosynthesis. This pathway is the main metabolic pathway in neutrophils, congenital deficiency in the pathway produces sensitivity to infection.
Alternative metabolic route to Embden Meyerhof pathway for breakdown of glucose.
(18 Nov 1997)
hexose monphosphate pathway A metabolic pathway present in a wide range of prokaryotic and eukaryotic microorganisms as well as in plants and animals, it involves the oxidative decarboxylation of glucose-6-phosphate, via 6 phosphogluconate, to ribulose 5-phosphate, followed by a series of reversible, non-oxidative interconversions whereby hexose and triose phosphates are formed from pentose phosphates.
(09 Oct 1997)
secondary sensory cortex A cortical region occupying the parietal operculum (upper lip of the lateral sulcus) closely posterior to the foot of the postcentral gyrus; like the primary somatic-sensory cortex of the postcentral gyrus, this region receives sensory impulses originating in face, trunk, and limbs; projections to the s.s.c. Are from the ventral basal complex (ventral posteromedial and posterolateral thalamic nuclei) and from the primary somesthetic cortex.
(05 Mar 2000)
secondary sensory nuclei Nuclei terminales, collective term indicating those nerve cell groups in the rhombencephalon and spinal cord in which the afferent fibres of the spinal and cranial nerves terminate.
Synonym: nuclei terminationis, secondary sensory nuclei.
(05 Mar 2000)
sensory <otolaryngology> Pertaining to or subserving sensation.
Origin: L. Sensorius
(18 Nov 1997)
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