| physiologic sclerosis | A slowly progressive sclerosis in the walls of the ovarian arteries which commences after puberty. Synonym: menstrual sclerosis, ovulational sclerosis. (05 Mar 2000) |
|---|---|
| Monckeberg's sclerosis | Arterial sclerosis involving the peripheral arteries, especially of the legs of older people, with deposition of calcium in the medial coat (pipestem arteries) but with little or no encroachment on the lumen. Synonym: medial arteriosclerosis, Monckeberg's calcification, Monckeberg's degeneration, Monckeberg's medial calcification, Monckeberg's sclerosis. (05 Mar 2000) |
| combined sclerosis | A subacute or chronic disorder of the spinal cord, such as that occurring in certain patients with vitamin B12 deficiency, characterised by a slight to moderate degree of gliosis in association with spongiform degeneration of the posterior and lateral columns. Synonym: combined sclerosis, combined system disease, funicular myelitis, Putnam-Dana syndrome, vitamin B12 neuropathy. (05 Mar 2000) |
| multiple sclerosis | <neurology> Neurodegenerative disease characterised by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in 3rd or 4th decade with intermittent progression over an extended period. Cause still uncertain. (18 Nov 1997) |
| posterior sclerosis | See Tabes dorsalis. (12 Dec 1998) |
| posterior spinal sclerosis | See Tabes dorsalis. (12 Dec 1998) |
| primary lateral sclerosis | Considered by many to be a subgroup of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski signs are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion. Synonym: lateral spinal sclerosis. (05 Mar 2000) |
| hippocampal sclerosis | A loss of cortical neurons and a reactive astrocytosis in the hippocampal regions of some persons with epilepsy. (05 Mar 2000) |
| skin lesions of tuberous sclerosis | <radiology> Adenoma sebaceum, Shagreen patches, periungual fibromata, ash-leaf hypopigmentation (12 Dec 1998) |
| nodular sclerosis | <cardiology, pathology> The progressive narrowing and hardening of the arteries over time. This is known to occur to some degree with aging, but other risk factors that accelerate this process have been identified. These factors include: high cholesterol, high blood pressure, smoking, diabetes and family history for atherosclerotic disease. (27 Sep 1997) |
| nuclear sclerosis | Increased refractivity of the central portion of the lens of the eye. See: nuclear cataract. (05 Mar 2000) |
| systemic sclerosis | <rheumatology> A multisystem disorder of unknown aetiology. It is characterised by fibrosis (scarring) of the skin, blood vessels and internal organs. Involvement of the gastrointestinal tract, heart, kidneys and lungs is common. (09 Jan 1998) |
| diffuse infantile familial sclerosis | <radiology> Dysmyelinating disease, autosomal recessive, usually presents by 1 yr, specific enzyme deficiency identified, rapid spontaneous nystagmus, poikilothermia Synonym: Krabbe leukodystrophy (12 Dec 1998) |
| disseminated sclerosis | <neurology> Neurodegenerative disease characterised by the gradual accumulation of focal plaques of demyelination particularly in the periventricular areas of the brain. Peripheral nerves are not affected. Onset usually in 3rd or 4th decade with intermittent progression over an extended period. Cause still uncertain. (18 Nov 1997) |
| idiopathic hypercalcaemic sclerosis of infants | See: idiopathic hypercalcaemia of infants. (05 Mar 2000) |