| saccharopine | HOOC(CH2)2CH(COOH)NH(CH2)4CH(NH2)COOH;a derivative of alpha-ketoglutarate and l-lysine that is an intermediate in l-lysine catabolism; elevated in cases of saccharopinuria. (05 Mar 2000) |
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| saccharopine dehydrogenase | Two enzymes that are used in the pathway of l-lysine catabolism; the first isoform catalyses the reversible conversion of l-lysine, alpha-ketoglutarate, and NADH to saccharopine and NAD+; the other isoform reversibly catalyses to conversion of saccharopine and NAD+ to l-glutamate, NADH, and l-alpha-aminoadipate d-saemialdehyde. A deficiency of one of these isoforms is associated with familial hyperlysinaemia and saccharopinuria. (05 Mar 2000) |
| saccharopine dehydrogenases | <enzyme> N-5-(1,3-dicarboxypropyl)-l-lysine:NAD(p)+ oxidoreductase (l-lysine-forming). Catalyses the oxidative cleavage of saccharopine to lysine plus ketoglutaric acid. Requires NAD; EC 1.5.1.8 requires NADP. Registry number: EC 1.5.1. (12 Dec 1998) |
| saccharopine oxidase | <enzyme> Flavoenzyme which catalyses the oxidative cleavage of saccharopine to delta-1-piper9deine-6-carboxylate, glutamate and h2o2 Registry number: EC 1.5.3.- (26 Jun 1999) |
| saccharopinuria | Elevated levels of saccharopine in the urine; associated with a variant of familial hyperlysinuria. (05 Mar 2000) |
| saccharopolyspora | A genus of gram-positive bacteria whose spores are round to oval and covered by a sheath. (12 Dec 1998) |
| saccharorrhoea | An obsolete term for glycosuria. Origin: saccharo-+ G. Rhoia, a flow (05 Mar 2000) |
| saccharose | <chemistry> Cane sugar; sucrose; also, in general, any one of the group of which saccharose, or sucrose proper, is the type. See Sucrose. Source: Websters Dictionary (01 Mar 1998) |
| saccharosuria | An obsolete term denoting the excretion of saccharose in the urine. Origin: saccharose + G. Ouron, urine (05 Mar 2000) |