| 영문 | coagulation necrosis | 한글 | 응고괴사 |
|---|---|---|---|
| 설명 | 세포의 죽음을 나타내는 형태학적 변화로서 괴사부위가 응고한 상태로 있는 것. 괴사세포는 호산성 덩어리로 보이며 적어도 수일간 세포의 기본 윤곽이 보존되기 때문에 조직구조를 식별할 수 있다. 대표적으로 허혈괴사를 들 수 있다. 경색과 허혈에 의한 저산소증시 심장근이나 콩팥에서 관찰되거나 전기 및 수은중독시 콩팥의 요세관에서 관찰되는 것으로 단백의 변성 후 남아있기 때문이다. 세포의 윤곽이 남아 있어 원래 조직의 구조를 형태학적으로 인식할 수 있는 것이 특징이다. |
||
| 영문 | caseation necrosis | 한글 | 치즈괴사, 건락괴사 |
|---|---|---|---|
| 설명 | 조직이 치즈와 같이 건조하고, 형태가 없는 덩어리로 변화하는 것으로 결핵감염 병터에서 볼 수 있는 독특한 괴사의 하나이다. |
||
| mosaic | <genetics> Descriptive of an organism that consists of two or more genetically distinct cell lines. (14 Nov 1997) |
|---|---|
| mosaic egg | <biology> At one time a distinction was drawn between those organisms in which the egg seemed to have a firmly committed fate map built in and regulating embryos. In the former, after the first cleavage one blastomere was committed to produce one set of tissues, the other blastomere a different set and removal of one blastomere led to the production of an incomplete embryo. This was particularly obvious in mollusc development where one blastomere had the polar lobe material. This early differentiation (or determination) of blastomeres for particular fates was in distinction to regulating embryos in which the removal of one blastomere did not matter, the other blastomere compensating and producing a full set of tissues. The distinction is, however, only based upon the timing of differentiative events and within a few divisions the regulating embryo also becomes a mosaic of determined cells. (18 Nov 1997) |
| mosaic fundus | A normal fundus to which a deeply pigmented choroid gives the appearance of dark polygonal areas between the choroidal vessels, especially in the periphery. Synonym: fundus tigre, leopard fundus, leopard retina, mosaic fundus, tigroid fundus, tigroid retina. (05 Mar 2000) |
| mosaic inheritance | Inheritance in which the paternal influence is dominant in one group of cells and the maternal in another. Compare: lyonization. (05 Mar 2000) |
| mosaic pattern | On high-resolution CT scans of the lungs, a pattern of brighter and darker regions corresponding to differences in perfusion or aeration; found in some cases of chronic thromboembolism or of bronchiolitis obliterans. Compare: oligaemia. (05 Mar 2000) |
| mosaic viruses | Viruses which produce a mottled appearance of the leaves of plants. (12 Dec 1998) |
| fluid mosaic model | A model used to conceptualise cell membranes, in it, the membranesare described as a structually and functionally asymmetric lipidbilayer studded with embedded proteins that aid in cross-membrane transport. (09 Oct 1997) |
| acute tubular necrosis | <nephrology> A kidney disorder that results in damage to the renal tubule cells leading to acute renal failure. Acute tubular necrosis can result from any condition which deprives the kidney of oxygen (ischaemia). Acute tubular necrosis may occur as a complication of shock, trauma or sepsis. Conditions such as diabetes or liver disease can predispose people to the development of acute tubular necrosis. Certain medications (for example aminoglycosides, amphotericin B, cyclosporine) are known to cause acute tubular necrosis as a toxic side effect. Radiopaque contrast dyes, used in some radiologic procedures, may also result in acute tubular necrosis as a rare complication from contrast dye use. Acronym: ATN (13 Nov 1997) |
| aseptic necrosis | <orthopaedics, pathology> Condition in which poor blood supply to an area of bone leads to bone death. Also called avascular necrosis and osteonecrosis. (12 Dec 1998) |
| avascular necrosis | <radiology> Aetiology (PLASTIC RAGS): P pancreatitis, L lupus, A alcohol, S steroids, T trauma, I idiopathic, infection, C caisson disease, collagen vascular disease, R radiation, rheumatoid arthritis, A amyloid, G Gaucher disease, S sickle cell disease findings: sclerosis, crescent sign, collapse (e.g., of femoral head) see also: staging (12 Dec 1998) |
| avascular necrosis staging | <radiology> Stage CT/X-ray bone scan I - cold/hot spot II sclerotic focus with osteopenic ring III crescent sign (subchondral lucency) IV articular collapse flattening of femoral head sensitivity 86% 78% specificity 79% 75% see also: avascular necrosis (AVN) (12 Dec 1998) |
| bridging hepatic necrosis | Area of liver necrosis which bridges adjacent portal areas and central veins; subsequent post-necrotic collapse and fibrosis is likely to result in cirrhosis. (05 Mar 2000) |
| p60 tumour necrosis factor receptor-associated kinase | <enzyme> Interacts with and causes phosphorylation of the cytoplasmic domain of the tnf receptor Registry number: EC 2.7.10.- Synonym: p60 tnf receptor-associated kinase, p60-trak (26 Jun 1999) |
| papillary necrosis | <radiology> Mnemonic: POST CARD, P pyelonephritis, O obstruction, S sickle cell disease, T TB, C cirrhosis (EtOH), A analgesics (phenacetin and aspirin), R renal vein thrombosis, D diabetes (12 Dec 1998) |
| receptors, tumour necrosis factor | Cell surface receptors that bind tumour necrosis factor and trigger changes which influence the behaviour of cells. The two recognised tumour necrosis factor receptors are designated alpha and beta receptors. Both receptors bind both alpha and beta tumour necrosis factors with high affinity, and both are members of the nerve growth factor receptor family. (12 Dec 1998) |