| rheumatoid factor | Complex of IgG and anti-igG formed in joints in rheumatoid arthritis. Serum rheumatoid factors are more usually formed from IgM antibodies directed against IgG. (18 Nov 1997) |
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| rheumatoid factors | Antibodies in the serum of individuals with rheumatoid arthritis that react with antigenic determinants or immunoglobulins that enhance agglutination of suspended particles coated with pooled human gamma-globulin. Rheumatoid factors also occur in other autoimmune and certain infectious diseases. (05 Mar 2000) |
| rheumatoid lung disease | <radiology> Pleural effusion, most common finding, seen mostly in males (although RA more common in females), diffuse interstitial fibrosis, necrobiotic nodules, Caplan syndrome, nodules and pneumoeritis and hypertension (12 Dec 1998) |
| rheumatoid nodule | Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterised histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes. (12 Dec 1998) |
| rheumatoid nodules | rheumatoid nodules are firm lumps in the skin of patients with rheumatoid arthritis that usually occur in pressure points of the body, most commonly the elbows (12 Dec 1998) |
| rheumatoid spondylitis | <rheumatology> A polyarthritis involving the spine, which is characterised by progressive, painful stiffening of the joints and ligaments. It almost exclusively affects young men. Interestingly the disease seems to be associated with HLA B27, those with this histocompatability antigen are 300 times more likely to get the disease, 90% of sufferers have HLA B27 (18 Nov 1997) |
| systemic-onset juvenile rheumatoid arthritis | <rheumatology> A form of joint disease, arthritis, that presents with systemic upset. Clinical signs: high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis itself may not be immediately apparent but once apparent, it may persist after the systemic symptoms have resolved. Synonym: Still's disease. (03 Jul 1999) |
| juvenile rheumatoid arthritis | <pathology> Juvenile rheumatoid arthritis (JRA) is a form of rheumatoid arthritis in children that generally occurs prior to age 16. In contrast with the adult type, a fever is more pronounced. Cardiac involvement with pericarditis is more common. The arthritis favors one or more large joints and can interfere with normal bone growth. A positive rheumatoid factor is seen more uncommonly in this form of arthritis. Treatment is similar to the adult form of the disease. Up to 75% recover with treatment. Less than 10% are severely disabled by JRA. (27 Sep 1997) |
| juvenile rheumatoid arthritis, systemic-onset | Also known as systemic-onset juvenile chronic arthritis. Still's disease presents with systemic (bodywide) illness including high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis may not be immediately apparent but it does always surface and it may persists long after the systemic symptoms are gone. (12 Dec 1998) |
| factor, rheumatoid | Rheumatoid factor is an antibody that is measurable in the blood. It is commonly used as a blood test for the diagnosis of rheumatoid arthritis. Rheumatoid factor is present in about 80% of adults (but a much lower proportion of children) with rheumatoid arthritis. It is also present in patients with other connective tissue diseases (such as systemic lupus erythematosus) and in some with infectious diseases (such as infectious hepatitis). (12 Dec 1998) |
| actinic dermatitis | Dermatitis caused or elicited by exposure to sunlight; may be phototoxic or photoallergic, and can result from topical application, ingestion, inhalation, or injection of mediating phototoxic or photoallergic material. See: photosensitization. Synonym: actinic dermatitis, actinodermatitis. Origin: photo-+ G. Derma, skin, + -itis, inflammation (05 Mar 2000) |
| allergic contact dermatitis | A delayed type IV allergic reaction of the skin with varying degrees of erythema, oedema, and vesiculation resulting from cutaneous contact with a specific allergen. Synonym: contact allergy. (05 Mar 2000) |
| ancylostoma dermatitis | Cutaneous larva migrans caused by larvae of hookworms. Synonym: ancylostoma dermatitis, ancylostomiasis cutis, coolie itch, dew itch, ground itch, swamp itch, swimmer's itch, toe itch, water itch, water sore. (05 Mar 2000) |
| atopic dermatitis | <dermatology> A type of immune-mediated (allergic) inflammatory skin disorder that results in a itchy rash. See: atopic eczema. (27 Sep 1997) |
| berloque dermatitis | Berlock dermatitis, a type of photosensitization resulting in deep brown pigmentation on exposure to sunlight after application of bergamot oil and other essential oils in perfume. (05 Mar 2000) |