| juvenile rheumatoid arthritis | <pathology> Juvenile rheumatoid arthritis (JRA) is a form of rheumatoid arthritis in children that generally occurs prior to age 16. In contrast with the adult type, a fever is more pronounced. Cardiac involvement with pericarditis is more common. The arthritis favors one or more large joints and can interfere with normal bone growth. A positive rheumatoid factor is seen more uncommonly in this form of arthritis. Treatment is similar to the adult form of the disease. Up to 75% recover with treatment. Less than 10% are severely disabled by JRA. (27 Sep 1997) |
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| juvenile rheumatoid arthritis, systemic-onset | Also known as systemic-onset juvenile chronic arthritis. Still's disease presents with systemic (bodywide) illness including high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis may not be immediately apparent but it does always surface and it may persists long after the systemic symptoms are gone. (12 Dec 1998) |
| factor, rheumatoid | Rheumatoid factor is an antibody that is measurable in the blood. It is commonly used as a blood test for the diagnosis of rheumatoid arthritis. Rheumatoid factor is present in about 80% of adults (but a much lower proportion of children) with rheumatoid arthritis. It is also present in patients with other connective tissue diseases (such as systemic lupus erythematosus) and in some with infectious diseases (such as infectious hepatitis). (12 Dec 1998) |
| apical interstitial lung disease | <radiology> A radiological diagnosis where fibrosis is seen in the apices (upper sections) of the lungs. Likely causes include: cystic fibrosis, ankylosing spondylitis, sarcoidosis, silicosis, eosinophlic granuloma, TB and fungus, particularly aspergillus infection. (25 Jun 1999) |
| asbestos lung disease | <radiology> Pleural plaques, earliest finding, may be only evidence, parietal pleura, 15-20 yrs after exposure, calcified after ca. 30 yrs, asbestosis, interstitial lung disease, perihilar regions to lung bases, shaggy heart, no cavitation or progressive massive fibrosis as in silicosis, crocidolite (blue) form most carcinogenic, associated with: malignant pleural mesothelioma, peritoneal mesothelioma, GI-tract malignancy (12 Dec 1998) |
| basilar interstitial lung disease | <radiology> B bronchiectasis, A asbestosis, D drugs / DIP, L lymphangitic metastasis / LAM, A aspiration, S sarcoidosis, S scleroderma (12 Dec 1998) |
| parasitic eosinophilic lung disease | <radiology> All are metazoans (mostly nematodes), Ascaris, Strongyloides, Ancyclostoma, Schistosoma, tropical pulmonary eosinophilia, pulmonary larva migrans (12 Dec 1998) |
| drug-induced eosinophilic lung disease | <radiology> Diffuse reticular pattern: nitrofurantoin, Loeffler-like pattern: penicillin, sulfonamides, ASA, para-ASA, imipramine, HCTZ, cromolyn sodium see: eosinophilic lung disease (12 Dec 1998) |
| interstitial lung disease | <chest medicine> A group of lung disorders which result in scarring and dysfunction of the alveolus (air sac) in the lung. This results in poor oxygen diffusion from the air into the bloodstream. Widespread inflammation in the lung leads to fibrosis (scarring). Causes include chronic exposure to organic and inorganic dusts, fumes, vapors, radiation, medications and certain lung infections. Examples include asbestosis, silicosis, coal worker's pneumoconiosis and diffuse interstitial fibrosis. Smoking increases the risk in all cases. (27 Sep 1997) |
| interstitial lung disease with increased volume | <radiology> Cystic fibrosis (CF), eosinophilic granuloma (EG), lymphangioleiomyomatosis (LAM) (12 Dec 1998) |
| obstructive lung disease | <chest medicine> A form of lung disease that manifests as acute or chronic, narrowing or blockage of the smaller airways in the lungs, causing increased resistance to airflow in the bronchial tubes (for example asthma, silicosis, chronic obstructive pulmonary disease from smoking). (27 Sep 1997) |
| occupational lung disease | Fibrosis and scarring of the lungs secondary to the repeated inhalation of dust associated with some occupation. Examples include silica, asbestos and coal dust exposure. (27 Sep 1997) |
| eosinophilic lung disease | <radiology> Idiopathic: Loeffler pneumonia, chronic eosinophilic pneumonia, hypereosinophilic syndrome, specific: drugs (e.g., nitrofurantoin), parasites, fungi (ABPA, bronchocentric granulomatosis), vasculitis / granulomatosis: Wegener's granulomatosis, polyarteritis nodosa, sarcoidal angiitis (12 Dec 1998) |
| lung fluke disease | Infection with the lung fluke, Clonorchis sinensis. (05 Mar 2000) |
| air-conditioner lung | An extrinsic allergic alveolitis caused by forced air contaminated by thermophilic actinomycetes and other organisms. (05 Mar 2000) |