| ABCDES | abnormal alignment, bones-periarticular osteoporosis, cartilage-joint space loss, deformities, margi... |
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| CHRONIC | chronic disease, rheumatoid arthritis, neoplasms, infections, cryoglobulinemia [conditions in which ... |
| Gc globulin | Group-specific complement globulin |
| CBG | capillary blood gases; coronary bypass graft; corticosteroid-binding globulin; cortisol-binding glob... |
| JRA | Juvenile Rheumatoid Arthritis; 연소기 류마토이드 관절염 = Juvenile Chronic Arthritis; 연소기 만성 관절... |
| rheumatoid spondylitis | <rheumatology> A polyarthritis involving the spine, which is characterised by progressive, painful stiffening of the joints and ligaments. It almost exclusively affects young men. Interestingly the disease seems to be associated with HLA B27, those with this histocompatability antigen are 300 times more likely to get the disease, 90% of sufferers have HLA B27 (18 Nov 1997) |
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| systemic-onset juvenile rheumatoid arthritis | <rheumatology> A form of joint disease, arthritis, that presents with systemic upset. Clinical signs: high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis itself may not be immediately apparent but once apparent, it may persist after the systemic symptoms have resolved. Synonym: Still's disease. (03 Jul 1999) |
| juvenile rheumatoid arthritis | <pathology> Juvenile rheumatoid arthritis (JRA) is a form of rheumatoid arthritis in children that generally occurs prior to age 16. In contrast with the adult type, a fever is more pronounced. Cardiac involvement with pericarditis is more common. The arthritis favors one or more large joints and can interfere with normal bone growth. A positive rheumatoid factor is seen more uncommonly in this form of arthritis. Treatment is similar to the adult form of the disease. Up to 75% recover with treatment. Less than 10% are severely disabled by JRA. (27 Sep 1997) |
| juvenile rheumatoid arthritis, systemic-onset | Also known as systemic-onset juvenile chronic arthritis. Still's disease presents with systemic (bodywide) illness including high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis may not be immediately apparent but it does always surface and it may persists long after the systemic symptoms are gone. (12 Dec 1998) |
| factor, rheumatoid | Rheumatoid factor is an antibody that is measurable in the blood. It is commonly used as a blood test for the diagnosis of rheumatoid arthritis. Rheumatoid factor is present in about 80% of adults (but a much lower proportion of children) with rheumatoid arthritis. It is also present in patients with other connective tissue diseases (such as systemic lupus erythematosus) and in some with infectious diseases (such as infectious hepatitis). (12 Dec 1998) |
| accelerator globulin | Globulin in serum that promotes the conversion of prothrombin to thrombin in the presence of thromboplastin and ionised calcium. See: factor Va, factor V, serum accelerator globulin. (05 Mar 2000) |
| albumin-globulin ratio | The ratio of albumin to globulin in the serum or in the urine in kidney disease; the normal ratio in the serum is approximately 1.55. (05 Mar 2000) |
| alpha-globulin | <protein> The serum globulins with the most rapid electrophoretic migration, further subdivided into faster alpha(1)- and slower alpha(2)-globulins. (12 Dec 1998) |
| antihemophilic globulin | A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so females can be silent carriers without symptoms and males can be haemophiliacs. (12 Dec 1998) |
| antihemophilic globulin A | A coagulation (clotting) factor. Classic haemophilia (haemophilia A) is due to a congenital deficiency in the amount (or activity) of factor VIII. Factor VIII is also known as antihemophiliac factor (AHF) or antihemophiliac globulin (AHG). The gene for factor VIII (that for classic haemophilia) is on the X chromosome so females can be silent carriers without symptoms and males can be haemophiliacs. (12 Dec 1998) |
| antihemophilic globulin B | <chemical> Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, ixa, forms a complex with factor viii and calcium on platelet factor 3 to activate factor x to xa. Deficiency of factor ix results in christmas disease (haemophilia b). Chemical name: Blood-coagulation factor IX (12 Dec 1998) |
| antihuman globulin | Serum from a rabbit or other animal previously immunised with purified human globulin to prepare antibodies directed against IgG and complement; used in the direct and indirect Coombs' tests. Synonym: Coombs' serum. (05 Mar 2000) |
| antilymphocyte globulin | <protein> Antibodies which attach to and destroy lymphocytes. This may be used clinically by injection into a vein, for example in aplastic anaemia. (13 Nov 1997) |
| b1C globulin | The third component (C3) of complement. See: component of complement. (05 Mar 2000) |
| b1E globulin | The fourth component (C4) of complement. See: component of complement. (05 Mar 2000) |