| RIA | radioimmunoassay; reversible ischemic attack |
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| RIND | reversible ischemic neurologic deficit |
| ROAD | reversible obstructive airways disease |
| RSC | rat spleen cell; rested state contraction; reversible sickle-cell; right subclavian |
| TRINS | totally reversible ischemic neurological symptoms |
| minimal-change nephrotic syndrome | <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown. Risk factors include a history for a immune disorder, recent immunisation or a bee sting. Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented. Synonym: lipoid nephrosis (27 Sep 1997) |
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| conformational change | <cell biology> Alteration in the shape usually the tertiary structure of a protein as a result of alteration in the environment pH, temperature, ionic strength) or the binding of a ligand (to a receptor) or binding of substrate (to an enzyme). (18 Nov 1997) |
| Crooke's hyaline change | Replacement of cytoplasmic granules of basophil cells of the anterior pituitary by homogenous hyaline material; a characteristic finding in Cushing's syndrome, but usually not present in the cells of a basophil adenoma. Synonym: Crooke's hyaline degeneration. (05 Mar 2000) |
| social change | Social process whereby the values, attitudes, or institutions of society, such as education, family, religion, and industry become modified. It includes both the natural process and action programs initiated by members of the community. (12 Dec 1998) |
| enthalpy change | <chemistry> In a reaction, this is more or less equal to the difference between the energy put into breaking bonds and the enery gained from new bond formation. (13 Oct 1997) |
| epigenetic change | <biology> Any changes in an organism brought about by alterations in the action of genes are called epigenetic changes. Epigenetic transformation refers to those processes which cause normal cells to become tumour cells without the occurrence of any mutations. (07 May 1998) |
| fatty change | The appearance of microscopically visible droplets of fat in the cytoplasm of cells. See: fatty degeneration. Synonym: fatty change. (05 Mar 2000) |
| life change events | Those occurrences, including social, psychological, and environmental, which require an adjustment or effect a change in an individual's pattern of living. (12 Dec 1998) |